#Genomic #signatures and #host #adaptation of #H5N1 clade 2.3.4.4b: A call for global #surveillance and multi-target antiviral strategies, https://etidiohnew.blogspot.com/2025/04/genomic-signatures-and-host-adaptation.html

#KnowledgeByte: #Genomic #Grammar is a set of associated components for each disease. It can help identify important differences and common aspects in a specific group of diseases.

https://knowledgezone.co.in/posts/Genomic-Language-and-Grammar-660a4bdaa9d5187c1262c9ed

Assumptions about #genomic #diversity may create #conservation illusions of population health.

#extinction

https://phys.org/news/2025-03-assumptions-genomic-diversity-illusions-population.html

Multi-trait ensemble #genomic prediction and simulations of recurrent selection highlight importance of complex trait genetic architecture for long-term genetic gains in #wheat
Story: https://botany.one/2023/03/unlocking-the-secret-to-breeding-high-yielding-protein-rich-wheat/ via @botanyone
Research: https://doi.org/10.1093/insilicoplants/diad002 from Nick Fradgley, Keith A Gardner, Alison R Bentley, Phil Howell, Ian J Mackay, Michael F Scott, Richard Mott, James Cockram
#PlantScience

We are delighted to announce the selected organisations for a new pilot programme of the #OpenDataEditor. We look forward to seeing ODE in action to ensure the quality of #genomic, #infrastructure and #climatedata in such diverse parts of the world.

https://buff.ly/mVeQ4nU

My day job is all about #genes, so I applaud the #genomic revolution in #paleontology and #evolutionary #biology. But #evolution really is more than a shift in #allele frequencies over time. It's also change in the #phenotypes those alleles produce, and their #interaction with the world around them.

https://www.cambridge.org/core/journals/paleobiology/article/morphological-evolution-in-a-time-of-phenomics/4A7E3BC775855EC40DE03F9EE567D22A

So I'm equally excited about the #quantitative revolution in describing and cataloguing #traits which until recently could only be analyzed #qualitatively. There's a whole new window opening into the history of life.

#Ontario, Canada peeps or anyone have insight into why there was a sudden stop of uploading Ontario COVID #genomic sequence data to #GISAID? Last sequences dated Feb. 12, 2025 and nothing since. There was still 57-83 sequences a day being uploaded before that.

Now only a small # of sequences coming from NB & Quebec and periodically a few from AB, BC, and NS for all of Canada. You can see the big drop in Canada sequences when ON stopped submitting so very difficult to track what is going on.1/

Simultaneous #aerobic and #anaerobic #respiration in a Yellowstone #thermophile challenges scientific norms

#mightymicrobes #extremophiles #chemolithotroph #genomic #metabolism #bacteria #archea #funded_by_NASA #funded_by_us

https://phys.org/news/2025-03-simultaneous-aerobic-anaerobic-respiration-yellowstone.html

PhD from Sept 2025: Graph Neural Networks linking #pathways and #ontologies, trained using #genomic and functional genomic data to understand #cardiometabolic disorders . More at https://tinyurl.com/GNNEgid
#deeplearning #diabetes #obesity

Introducing #Evo_2, a predictive and generative #genomic #AI for all domains of #life.

#evolution #diversity #OpenGenome2 #funded#by_NSF #funded_by_US

https://phys.org/news/2025-03-evo-generative-genomic-ai-domains.html

Does anyone use #duckdb as a database for #genomic sequence data, i.e. sample metadata, fastq & vcf file paths etc. and have it sit in a s3 bucket or ftp server to then query from, both within cloud compute and from local compute?

Phylogenetic #discordance cannot identify #genomic #reassortment events: a case study with the avian #influenza virus #H5Nx, https://etidiohnew.blogspot.com/2025/03/phylogenetic-discordance-cannot.html

#Genomic tools reveal health insights for endangered Indiana #bats.

#wildlife #microbiome #parasites #Eimeria #faeces

https://phys.org/news/2025-02-genomic-tools-reveal-health-insights.html

The third winner of our #OpenResearch Award is Nadja Brait and team presenting:

"An open-source solution for finding ancient viral integrations in #genomic #data".

Read more about their research:
https://www.rug.nl/research/openscience/open-research-award/brait

They couldn't make it to the event, but prerecorded a video. Thank you !

#Chromatin fiber's #genomic 'memory' governs the building blocks of life, study reveals.

#transcription #nucleosome

https://phys.org/news/2025-02-chromatin-fiber-genomic-memory-blocks.html

#Corn's ancient ancestors are calling: #Genomic encyclopedia sheds light on #domestication 9,000 years ago.

#maize #teosinte #MaizeCODE #ENCODE #enhancers

https://phys.org/news/2025-02-corn-ancient-ancestors-genomic-encyclopedia.html

#Genomic evidence confirms #white_shark #liver is on Australian #killer_whales' menu

menu https://phys.org/news/2025-01-genomic-evidence-white-shark-liver.html

#Genomic analyses reveal #human activity's vital role in #Amazonian species' #genetic makeup.

#conservation #biodiversity #Indigenous_management #Bertholletia

https://phys.org/news/2025-01-genomic-analyses-reveal-human-vital.html

Population #genomic analysis uncovers complex #breeding history of celery

#agriculture #domestication #crops

https://phys.org/news/2025-01-population-genomic-analysis-uncovers-complex.html

#Embryo editing debate is back:

Heritable polygenic editing: next frontier in #genomic #medicine?

In it Visscher suggest editing 10 bits of #DNA could reduce the prevalence of #Alzheimer’s or #schizophrenia by nearly 10-fold. Another 10 edits could diminish coronary artery #disease more than 30-fold, and 10 more edits could cut type 2 #diabetes by roughly 60-fold.
But doing so would be controversial, both at a scientific and moral level.
https://www.nature.com/articles/s41586-024-08300-4 #genes #genetic #geneticediting