@RandamuMaki @delta great that this works, though @liaizon opened an issue on the desktop repo with your report and I would like to help getting it solved/closed.
Could you try to download and run https://github.com/chatmail/core/releases/download/v1.156.2/deltachat-rpc-server-x86_64-linux ? that't the dc core binary that desktop failed to load/find in your screenshot.
If it doesn't work it would be interesting to know any clues to why and wether the newest core from https://github.com/chatmail/core/releases still has the problem.