Fosstodon

Hambone FakenamingtonI rarely splice sitting on the ground but this afternoon I didn't feel like carrying the table to the chamber.<a href="https://fosstodon.org/tags/splicing" class="mention hashtag" rel="tag">#splicing</a> <a href="https://fosstodon.org/tags/fibre" class="mention hashtag" rel="tag">#fibre</a> <a href="https://fosstodon.org/tags/FibreBroadband" class="mention hashtag" rel="tag">#FibreBroadband</a> <a href="https://fosstodon.org/tags/altnet" class="mention hashtag" rel="tag">#altnet</a> <a href="https://fosstodon.org/tags/altnets" class="mention hashtag" rel="tag">#altnets</a>

Sustainable SailingA cold North East wind today (over 20kts) so we did a quick trip to our shipping container, then Jane has been <a href="https://mas.to/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> the first <a href="https://mas.to/tags/dyneema" class="mention hashtag" rel="nofollow noopener" target="_blank">#dyneema</a> main mast chainplate loop (much harder splicing 12mm than 9mm). After some writing for work I've been working on wiring diagrams (learning and using <a href="https://mas.to/tags/QElectroTech" class="mention hashtag" rel="nofollow noopener" target="_blank">#QElectroTech</a>). I like that I can pretty easily create basic custom elements such as our Batteries, <a href="https://mas.to/tags/Victron" class="mention hashtag" rel="nofollow noopener" target="_blank">#Victron</a> boxes etc.

Hambone Fakenamington<a href="https://fosstodon.org/tags/SilentSunday" class="mention hashtag" rel="tag">#SilentSunday</a> <a href="https://fosstodon.org/tags/Splicing" class="mention hashtag" rel="tag">#Splicing</a> <a href="https://fosstodon.org/tags/RuralBroadband" class="mention hashtag" rel="tag">#RuralBroadband</a> <a href="https://fosstodon.org/tags/Altnet" class="mention hashtag" rel="tag">#Altnet</a> <a href="https://fosstodon.org/tags/Altnets" class="mention hashtag" rel="tag">#Altnets</a> <a href="https://fosstodon.org/tags/UK" class="mention hashtag" rel="tag">#UK</a> <a href="https://fosstodon.org/tags/FibreBroadband" class="mention hashtag" rel="tag">#FibreBroadband</a> <a href="https://fosstodon.org/tags/FTTP" class="mention hashtag" rel="tag">#FTTP</a>

Hambone FakenamingtonAnd to follow up.. Tuesday evening (not quite such a late one).<a href="https://fosstodon.org/tags/Splicing" class="mention hashtag" rel="tag">#Splicing</a> <a href="https://fosstodon.org/tags/fibre" class="mention hashtag" rel="tag">#fibre</a> <a href="https://fosstodon.org/tags/fiber" class="mention hashtag" rel="tag">#fiber</a> <a href="https://fosstodon.org/tags/altnet" class="mention hashtag" rel="tag">#altnet</a> <a href="https://fosstodon.org/tags/altnets" class="mention hashtag" rel="tag">#altnets</a> <a href="https://fosstodon.org/tags/RuralBroadband" class="mention hashtag" rel="tag">#RuralBroadband</a>

Hambone FakenamingtonWorked into the early evening .. but got to see this from my work site.<a href="https://fosstodon.org/tags/Splicing" class="mention hashtag" rel="tag">#Splicing</a> <a href="https://fosstodon.org/tags/altnet" class="mention hashtag" rel="tag">#altnet</a> <a href="https://fosstodon.org/tags/altnets" class="mention hashtag" rel="tag">#altnets</a> <a href="https://fosstodon.org/tags/fibre" class="mention hashtag" rel="tag">#fibre</a> <a href="https://fosstodon.org/tags/FibreSplicing" class="mention hashtag" rel="tag">#FibreSplicing</a> <a href="https://fosstodon.org/tags/sunset" class="mention hashtag" rel="tag">#sunset</a> <a href="https://fosstodon.org/tags/uk" class="mention hashtag" rel="tag">#uk</a> <a href="https://fosstodon.org/tags/SilentMonday" class="mention hashtag" rel="tag">#SilentMonday</a> <a href="https://fosstodon.org/tags/RuralBroadband" class="mention hashtag" rel="tag">#RuralBroadband</a> <a href="https://fosstodon.org/tags/Rural" class="mention hashtag" rel="tag">#Rural</a> <a href="https://fosstodon.org/tags/RuralEngland" class="mention hashtag" rel="tag">#RuralEngland</a>

Knowledge ZoneIs the <a href="https://mstdn.social/tags/World" class="mention hashtag" rel="nofollow noopener" target="_blank">#World</a> Ready? - #2025 <a href="https://mstdn.social/tags/SolarStorm" class="mention hashtag" rel="nofollow noopener" target="_blank">#SolarStorm</a> : Medium<a href="https://mstdn.social/tags/MIT" class="mention hashtag" rel="nofollow noopener" target="_blank">#MIT</a> <a href="https://mstdn.social/tags/Biologists" class="mention hashtag" rel="nofollow noopener" target="_blank">#Biologists</a> <a href="https://mstdn.social/tags/Discover" class="mention hashtag" rel="nofollow noopener" target="_blank">#Discover</a> a new type of control over <a href="https://mstdn.social/tags/RNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#RNA</a> <a href="https://mstdn.social/tags/Splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#Splicing</a> : MIT<a href="https://mstdn.social/tags/Physicists" class="mention hashtag" rel="nofollow noopener" target="_blank">#Physicists</a> capture a strange <a href="https://mstdn.social/tags/Fractal" class="mention hashtag" rel="nofollow noopener" target="_blank">#Fractal</a> ‘<a href="https://mstdn.social/tags/Butterfly" class="mention hashtag" rel="nofollow noopener" target="_blank">#Butterfly</a>’ for the first time : New SciCheck our latest <a href="https://mstdn.social/tags/KnowledgeLinks" class="mention hashtag" rel="nofollow noopener" target="_blank">#KnowledgeLinks</a><a href="https://knowledgezone.co.in/resources/bookmarks" rel="nofollow noopener" translate="no" target="_blank">https://knowledgezone.co.in/resources/bookmarks</a>

CellBioNewsBiologists discover a new type of control over <a href="https://scientificnetwork.de/tags/RNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#RNA</a> <a href="https://scientificnetwork.de/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a><a href="https://scientificnetwork.de/tags/spliceosome" class="mention hashtag" rel="nofollow noopener" target="_blank">#spliceosome</a> <a href="https://scientificnetwork.de/tags/U1" class="mention hashtag" rel="nofollow noopener" target="_blank">#U1</a> <a href="https://scientificnetwork.de/tags/snRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#snRNA</a> <a href="https://scientificnetwork.de/tags/LUC7" class="mention hashtag" rel="nofollow noopener" target="_blank">#LUC7</a> <a href="https://phys.org/news/2025-02-biologists-rna-splicing.html" rel="nofollow noopener" translate="no" target="_blank">https://phys.org/news/2025-02-biologists-rna-splicing.html</a>

ExtremeDullardCheap, low-effort, perfect filament splicing method <a href="https://toobnix.org/videos/watch/b1d3fcc7-3067-4cb8-84b7-5e19dc340f36" rel="nofollow noopener" translate="no" target="_blank">https://toobnix.org/videos/watch/b1d3fcc7-3067-4cb8-84b7-5e19dc340f36</a>

Pyrzout :vm:Undersea Cable Repair <a href="https://hackaday.com/2024/07/30/undersea-cable-repair/" rel="nofollow noopener" translate="no" target="_blank">https://hackaday.com/2024/07/30/undersea-cable-repair/</a> <a href="https://social.skynetcloud.site/tags/Engineering" class="mention hashtag" rel="nofollow noopener" target="_blank">#Engineering</a> <a href="https://social.skynetcloud.site/tags/OriginalArt" class="mention hashtag" rel="nofollow noopener" target="_blank">#OriginalArt</a> <a href="https://social.skynetcloud.site/tags/underwater" class="mention hashtag" rel="nofollow noopener" target="_blank">#underwater</a> <a href="https://social.skynetcloud.site/tags/Featured" class="mention hashtag" rel="nofollow noopener" target="_blank">#Featured</a> <a href="https://social.skynetcloud.site/tags/internet" class="mention hashtag" rel="nofollow noopener" target="_blank">#internet</a> <a href="https://social.skynetcloud.site/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> <a href="https://social.skynetcloud.site/tags/cable" class="mention hashtag" rel="nofollow noopener" target="_blank">#cable</a> <a href="https://social.skynetcloud.site/tags/ocean" class="mention hashtag" rel="nofollow noopener" target="_blank">#ocean</a> <a href="https://social.skynetcloud.site/tags/boat" class="mention hashtag" rel="nofollow noopener" target="_blank">#boat</a>

GeekProjects NewsUndersea Cable Repair <a href="https://hackaday.com/2024/07/30/undersea-cable-repair/" rel="nofollow noopener" translate="no" target="_blank">https://hackaday.com/2024/07/30/undersea-cable-repair/</a> <a href="https://geekprojects.com/tags/Engineering" class="mention hashtag" rel="nofollow noopener" target="_blank">#Engineering</a> <a href="https://geekprojects.com/tags/OriginalArt" class="mention hashtag" rel="nofollow noopener" target="_blank">#OriginalArt</a> <a href="https://geekprojects.com/tags/underwater" class="mention hashtag" rel="nofollow noopener" target="_blank">#underwater</a> <a href="https://geekprojects.com/tags/Featured" class="mention hashtag" rel="nofollow noopener" target="_blank">#Featured</a> <a href="https://geekprojects.com/tags/internet" class="mention hashtag" rel="nofollow noopener" target="_blank">#internet</a> <a href="https://geekprojects.com/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> <a href="https://geekprojects.com/tags/cable" class="mention hashtag" rel="nofollow noopener" target="_blank">#cable</a> <a href="https://geekprojects.com/tags/ocean" class="mention hashtag" rel="nofollow noopener" target="_blank">#ocean</a> <a href="https://geekprojects.com/tags/boat" class="mention hashtag" rel="nofollow noopener" target="_blank">#boat</a>

IT NewsUndersea Cable Repair - The bottom of the sea is a mysterious and inaccessible place, and anything unfortu... - <a href="https://hackaday.com/2024/07/30/undersea-cable-repair/" rel="nofollow noopener" translate="no" target="_blank">https://hackaday.com/2024/07/30/undersea-cable-repair/</a> <a href="https://schleuss.online/tags/engineering" class="mention hashtag" rel="nofollow noopener" target="_blank">#engineering</a> <a href="https://schleuss.online/tags/originalart" class="mention hashtag" rel="nofollow noopener" target="_blank">#originalart</a> <a href="https://schleuss.online/tags/underwater" class="mention hashtag" rel="nofollow noopener" target="_blank">#underwater</a> <a href="https://schleuss.online/tags/featured" class="mention hashtag" rel="nofollow noopener" target="_blank">#featured</a> <a href="https://schleuss.online/tags/internet" class="mention hashtag" rel="nofollow noopener" target="_blank">#internet</a> <a href="https://schleuss.online/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> <a href="https://schleuss.online/tags/cable" class="mention hashtag" rel="nofollow noopener" target="_blank">#cable</a> <a href="https://schleuss.online/tags/ocean" class="mention hashtag" rel="nofollow noopener" target="_blank">#ocean</a> <a href="https://schleuss.online/tags/boat" class="mention hashtag" rel="nofollow noopener" target="_blank">#boat</a>

Cosmin SaveanuA 6 months internship (M2) is open in our laboratory for January 2025 to work on <a href="https://framapiaf.org/tags/RNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#RNA</a>, the genetics and biochemistry of its <a href="https://framapiaf.org/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a>, export from the nucleus and degradation in the cytoplasm. With new tools and exciting preliminary results in <a href="https://framapiaf.org/tags/Cryptococcus" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cryptococcus</a> neoformans, an intron-rich and fascinating human <a href="https://framapiaf.org/tags/fungal" class="mention hashtag" rel="nofollow noopener" target="_blank">#fungal</a> pathogen.<a href="https://cosminribo.eu/posts/2024-07-m2topic/" rel="nofollow noopener" translate="no" target="_blank">https://cosminribo.eu/posts/2024-07-m2topic/</a>

katch wreck"Most importantly, by proving that the evolutionarily-conserved RNA core of splicing machines can recognize small molecules specifically, our work provides a solid basis for the rational design of splicing modulators not only against bacterial and organellar introns, but also against the human spliceosome, which is a validated drug target for the treatment of congenital diseases and cancers." <a href="https://mastodon.social/tags/spliceosome" class="mention hashtag" rel="nofollow noopener" target="_blank">#spliceosome</a> <a href="https://mastodon.social/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> <a href="https://mastodon.social/tags/intron" class="mention hashtag" rel="nofollow noopener" target="_blank">#intron</a> <a href="https://mastodon.social/tags/introns" class="mention hashtag" rel="nofollow noopener" target="_blank">#introns</a> <a href="https://mastodon.social/tags/transcription" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcription</a> <a href="https://mastodon.social/tags/ribonucleicAcid" class="mention hashtag" rel="nofollow noopener" target="_blank">#ribonucleicAcid</a> <a href="https://mastodon.social/tags/RNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#RNA</a><a href="https://www.nature.com/articles/s41467-024-48697-0" rel="nofollow noopener" translate="no" target="_blank">https://www.nature.com/articles/s41467-024-48697-0</a>

CellBioNews<a href="https://scientificnetwork.de/tags/Genes" class="mention hashtag" rel="nofollow noopener" target="_blank">#Genes</a> spatially organize for efficient <a href="https://scientificnetwork.de/tags/mRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#mRNA</a> <a href="https://scientificnetwork.de/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a>, study shows.<a href="https://scientificnetwork.de/tags/nuclear_speckles" class="mention hashtag" rel="nofollow noopener" target="_blank">#nuclear_speckles</a><a href="https://phys.org/news/2024-05-genes-spatially-efficient-mrna-splicing.html" rel="nofollow noopener" translate="no" target="_blank">https://phys.org/news/2024-05-genes-spatially-efficient-mrna-splicing.html</a>

CellBioNewsResearchers study role of <a href="https://scientificnetwork.de/tags/post_transcriptional" class="mention hashtag" rel="nofollow noopener" target="_blank">#post_transcriptional</a> <a href="https://scientificnetwork.de/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> in <a href="https://scientificnetwork.de/tags/plant" class="mention hashtag" rel="nofollow noopener" target="_blank">#plant</a> response to <a href="https://scientificnetwork.de/tags/light" class="mention hashtag" rel="nofollow noopener" target="_blank">#light</a>.<a href="https://scientificnetwork.de/tags/spliceosome" class="mention hashtag" rel="nofollow noopener" target="_blank">#spliceosome</a> <a href="https://scientificnetwork.de/tags/AtPRMT5" class="mention hashtag" rel="nofollow noopener" target="_blank">#AtPRMT5</a> <a href="https://scientificnetwork.de/tags/photosynthesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#photosynthesis</a> <a href="https://phys.org/news/2024-02-role-transcriptional-splicing-response.html" rel="nofollow noopener" translate="no" target="_blank">https://phys.org/news/2024-02-role-transcriptional-splicing-response.html</a>

The EMBO JournalHong Cheng and collaborators identify <a href="https://sciencemastodon.com/tags/SAP30BP" class="mention hashtag" rel="nofollow noopener" target="_blank">#SAP30BP</a> as a novel critical activator of <a href="https://sciencemastodon.com/tags/CDK11" class="mention hashtag" rel="nofollow noopener" target="_blank">#CDK11</a>-<a href="https://sciencemastodon.com/tags/CyclinL" class="mention hashtag" rel="nofollow noopener" target="_blank">#CyclinL</a> complexes, required of regulation of pre-mRNA <a href="https://sciencemastodon.com/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> in cells <a href="https://www.embopress.org/doi/full/10.15252/embj.2023114051" rel="nofollow noopener" translate="no" target="_blank">https://www.embopress.org/doi/full/10.15252/embj.2023114051</a>

Mathieu Quesnel-VallièresIf you wonder what splice isoforms exist for your gene(s) of interest, or if you are interested in exploring tissue/cancer-specific splicing, we have a new tool for that.<a href="https://genomic.social/tags/RNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#RNA</a> <a href="https://genomic.social/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> <a href="https://genomic.social/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#cancer</a><a href="https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad1043/7416386?login=false" rel="nofollow noopener" translate="no" target="_blank">https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad1043/7416386?login=false</a>

CavalliLabNice work on <a href="https://mastodon.social/tags/chromatin" class="mention hashtag" rel="nofollow noopener" target="_blank">#chromatin</a> and <a href="https://mastodon.social/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> by the lab of Gil Ast:Human histone H1 variants impact splicing outcome by controlling RNA polymerase II elongationMol Cell, <a href="https://doi.org/10.1016/j.molcel.2023.10.003" rel="nofollow noopener" translate="no" target="_blank">https://doi.org/10.1016/j.molcel.2023.10.003</a>

Stephen Matheson🌵🌲Julia Salzman from Stanford <a href="http://salzmanlab.stanford.edu/" rel="nofollow noopener" target="_blank">http://salzmanlab.stanford.edu/</a>now explaining SPLASH: Statistically Primary aLignment Agnostic Sequence HomingWe want to rapidly survey large <a href="https://fediscience.org/tags/genomic" class="mention hashtag" rel="nofollow noopener" target="_blank">#genomic</a> areas, for regulatory sites, <a href="https://fediscience.org/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a>, etc. How do we look at sequencing data today? Through a lens of alignment with reference genomes. This can fail (e.g. cancer cells with shattered genomes, <a href="https://fediscience.org/tags/V" class="mention hashtag" rel="nofollow noopener" target="_blank">#V</a>(D)J <a href="https://fediscience.org/tags/recombination" class="mention hashtag" rel="nofollow noopener" target="_blank">#recombination</a> in immune cells)Her metaphor: we need ground penetrating radar for <a href="https://fediscience.org/tags/genomics" class="mention hashtag" rel="nofollow noopener" target="_blank">#genomics</a> <a href="https://fediscience.org/tags/CSSingleCells23" class="mention hashtag" rel="nofollow noopener" target="_blank">#CSSingleCells23</a> 1/2

Gal Haimovich 😷🔬☣🏳️‍🌈🏳️‍⚧We are pleased to announce that registration to this year's annual meeting in memory of Prof. Yossi Sperling is now open, at the link below. The meeting will take place in the Lopatie Hall at the Weizmann Institute on 16 Oct, 2023. We will be celebrating local RNA science, and enjoy contributions from our two wonderful keynote speakers for this year - Marvin Tannenabum and Christin Mayr (see attached poster) <a href="https://fediscience.org/tags/RNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#RNA</a> <a href="https://fediscience.org/tags/mRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#mRNA</a> <a href="https://fediscience.org/tags/lncRNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#lncRNA</a> <a href="https://fediscience.org/tags/translation" class="mention hashtag" rel="nofollow noopener" target="_blank">#translation</a> <a href="https://fediscience.org/tags/splicing" class="mention hashtag" rel="nofollow noopener" target="_blank">#splicing</a> <a href="https://fediscience.org/tags/transcription" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcription</a> <a href="https://erez.weizmann.ac.il/apx/r/ws1/101/101/?P101_PKNS_CODE=2604" rel="nofollow noopener" target="_blank">https://erez.weizmann.ac.il/apx/r/ws1/101/101/?P101_PKNS_CODE=2604</a>

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