Exercise-mimicking drug sheds weight, boosts muscle activity in mice
"But the new drug, known as SLU-PP-332, doesn’t affect appetite or food intake. Nor does it cause mice to exercise more. Instead, the drug boosts a natural metabolic pathway that typically responds to exercise. In effect, the drug makes the body act like it is training for a marathon, leading to increased energy expenditure and faster metabolism of fat in the body.
“This compound is basically telling skeletal muscle to make the same changes you see during endurance training,” said Thomas Burris, a professor of pharmacy at UF who led the recent research into the new drug.
“When you treat mice with the drug, you can see that their whole body metabolism turns to using fatty acids, which is very similar to what people use when they are fasting or exercising,” Burris added. “And the animals start losing weight.”
#BetterLivingThruChemestry" #obesity #antiAging
https://news.ufl.edu/2023/09/exercise-mimicking-drug/