Johannes Köster<p><a href="https://fosstodon.org/tags/Varlociraptor" class="mention hashtag" rel="tag">#<span>Varlociraptor</span></a> 8.7.4 is released. It provides a major performance improvement, leading to potentially dramatically decreased computational complexity for certain event definitions containing fold changes. <a href="https://github.com/varlociraptor/varlociraptor/releases/tag/v8.7.4" target="_blank" rel="nofollow noopener" translate="no"><span class="invisible">https://</span><span class="ellipsis">github.com/varlociraptor/varlo</span><span class="invisible">ciraptor/releases/tag/v8.7.4</span></a><br /><a href="https://fosstodon.org/tags/variant_calling" class="mention hashtag" rel="tag">#<span>variant_calling</span></a> <a href="https://fosstodon.org/tags/genomics" class="mention hashtag" rel="tag">#<span>genomics</span></a></p>
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#Varlociraptor
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Johannes Köster<p>I have released a new version of <a href="https://fosstodon.org/tags/varlociraptor" class="mention hashtag" rel="tag">#<span>varlociraptor</span></a> with 3 new features.<br />1. model now better deals with PCR artifacts on single reads<br />2. a new HINTS field that gives insight into model decisions<br />3. multi-bam input for alignment property estimation</p><p><a href="https://varlociraptor.github.io" target="_blank" rel="nofollow noopener" translate="no"><span class="invisible">https://</span><span class="">varlociraptor.github.io</span><span class="invisible"></span></a></p>
Johannes Köster<p>I am happy to announce that I am seeking for a <a href="https://fosstodon.org/tags/postdoctoral" class="mention hashtag" rel="tag">#<span>postdoctoral</span></a> bioinformatician or computer scientist for a full, <a href="https://fosstodon.org/tags/permanent_position" class="mention hashtag" rel="tag">#<span>permanent_position</span></a> as a research fellow in my lab! Co-maintain popular <a href="https://fosstodon.org/tags/opensource" class="mention hashtag" rel="tag">#<span>opensource</span></a> projects like <a href="https://fosstodon.org/tags/Bioconda" class="mention hashtag" rel="tag">#<span>Bioconda</span></a>, <a href="https://fosstodon.org/tags/Snakemake" class="mention hashtag" rel="tag">#<span>Snakemake</span></a>, and <a href="https://fosstodon.org/tags/Varlociraptor" class="mention hashtag" rel="tag">#<span>Varlociraptor</span></a>!<br />Develop exciting, versatile, and sustainably maintained solutions that will shape the future of precision medicine and bioinformatics in general.</p><p><a href="https://koesterlab.github.io/#research-fellow-permanent" target="_blank" rel="nofollow noopener" translate="no"><span class="invisible">https://</span><span class="ellipsis">koesterlab.github.io/#research</span><span class="invisible">-fellow-permanent</span></a></p>
Johannes Köster<p><a href="https://fosstodon.org/tags/Varlociraptor" class="mention hashtag" rel="tag">#<span>Varlociraptor</span></a> 8.0 is released. It provides drastically improved support for multi-allelic sites and fixes a bug that has before let to some rare false positives. <a href="https://varlociraptor.github.io" target="_blank" rel="nofollow noopener" translate="no"><span class="invisible">https://</span><span class="">varlociraptor.github.io</span><span class="invisible"></span></a></p>
Johannes Köster<p>There were several new <a href="https://fosstodon.org/tags/varlociraptor" class="mention hashtag" rel="tag">#<span>varlociraptor</span></a> releases in the last weeks. We have added support for imprecise breakend pairs, added the ability to tune additional aspects of the model and improved the reporting. <a href="https://varlociraptor.github.io" target="_blank" rel="nofollow noopener" translate="no"><span class="invisible">https://</span><span class="">varlociraptor.github.io</span><span class="invisible"></span></a></p>
Johannes Köster<p>There have been a couple of new <a href="https://fosstodon.org/tags/Varlociraptor" class="mention hashtag" rel="tag">#<span>Varlociraptor</span></a> releases in the last weeks. The VAF estimates have been improved, and support for breakends without EVENT fields (only MATEID) has been added. <a href="https://varlociraptor.github.io" target="_blank" rel="nofollow noopener" translate="no"><span class="invisible">https://</span><span class="">varlociraptor.github.io</span><span class="invisible"></span></a> <a href="https://fosstodon.org/tags/variant_calling" class="mention hashtag" rel="tag">#<span>variant_calling</span></a></p>
Johannes Köster<p>Hi all. I am Johannes Köster, a computer scientist and bioinformatician working at the @unidue. I am developer of the widely used workflow management system <a href="https://fosstodon.org/tags/Snakemake" class="mention hashtag" rel="tag">#<span>Snakemake</span></a> and the genomic variant caller <a href="https://fosstodon.org/tags/Varlociraptor" class="mention hashtag" rel="tag">#<span>Varlociraptor</span></a>. Further I am the founder of the <a href="https://fosstodon.org/tags/Bioconda" class="mention hashtag" rel="tag">#<span>Bioconda</span></a> project which offers the largest collection of <a href="https://fosstodon.org/tags/Conda" class="mention hashtag" rel="tag">#<span>Conda</span></a> packages for bioinformatics software. <a href="https://fosstodon.org/tags/introduction" class="mention hashtag" rel="tag">#<span>introduction</span></a></p>
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