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#Tirzepatide

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Bret Mogilefsky<p>📈📉📈😩For those struggling with their weight and related health problems: Below I wrote up a thread about my brief experience so far with being prescribed the GLP1-agonist drugs <a href="https://hachyderm.io/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a> (aka <a href="https://hachyderm.io/tags/Ozempic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Ozempic</span></a> / <a href="https://hachyderm.io/tags/Wegovy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Wegovy</span></a>) and <a href="https://hachyderm.io/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> (aka <a href="https://hachyderm.io/tags/Mounjaro" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Mounjaro</span></a> / <a href="https://hachyderm.io/tags/Zepbound" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Zepbound</span></a>), and my struggle to get insurance coverage (boo <a href="https://hachyderm.io/tags/FEPBlue" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FEPBlue</span></a>! You suck!).</p><p>🧪🥼I also talk light science about a related experimental drug called <a href="https://hachyderm.io/tags/bimagrumab" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>bimagrumab</span></a> that I *might* be helping to test via a <a href="https://hachyderm.io/tags/ClinicalTrial" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ClinicalTrial</span></a>. It's pretty fascinating stuff!<br><a href="https://hachyderm.io/@mogul/114844234796648397" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">hachyderm.io/@mogul/1148442347</span><span class="invisible">96648397</span></a></p>
Douglas Edwards :neurodiv:<p><span class="h-card" translate="no"><a href="https://beige.party/@miffyhelen" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>miffyhelen</span></a></span> I'm type 2 diabetic AND an inpatient pharmacist. Ever since I started taking <a href="https://zeroes.ca/tags/incretin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>incretin</span></a> drugs — first <a href="https://zeroes.ca/tags/Bydureon" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Bydureon</span></a> (<a href="https://zeroes.ca/tags/exenatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>exenatide</span></a>), then <a href="https://zeroes.ca/tags/Ozempic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Ozempic</span></a> (<a href="https://zeroes.ca/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a>), and most recently <a href="https://zeroes.ca/tags/Mounjaro" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Mounjaro</span></a> (<a href="https://zeroes.ca/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a>) — it has transformed my experience of exercise. Before, I never understood how anyone could enjoy exercise. I suspect another diabetes drug of a different class, good old <a href="https://zeroes.ca/tags/metformin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>metformin</span></a>, is helping too. <a href="https://zeroes.ca/tags/Mounjaro" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Mounjaro</span></a>, especially, has made a world of difference. If you're not diabetic, <a href="https://zeroes.ca/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> is also available as a weight-loss drug under a different name (<a href="https://zeroes.ca/tags/Zepbound" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Zepbound</span></a>). And another <a href="https://zeroes.ca/tags/incretin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>incretin</span></a> drug, not approved yet, is on the horizon: <a href="https://zeroes.ca/tags/retatrutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>retatrutide</span></a>. From everything I've read about it, it should be the best of all.</p>
Christos Argyropoulos MD, PhD<p>We should talk about what hides under the clinical successes of <a href="https://med-mastodon.com/tags/glp1" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>glp1</span></a> e.g. <a href="https://med-mastodon.com/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> or <a href="https://med-mastodon.com/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a>. A paper published in the last 6 months suggests that the benefits (at least as the <a href="https://med-mastodon.com/tags/kidneys" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>kidneys</span></a>) are concerned are only partly (45%) explained by weight loss. What are we missing?</p>
Christos Argyropoulos MD PhD<p>We should talk about what hides under the clinical successes of <a href="https://mastodon.social/tags/glp1" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>glp1</span></a> e.g. <a href="https://mastodon.social/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> or <a href="https://mastodon.social/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a>. A paper published in the last 6 months suggests that the benefits (at least as the <a href="https://mastodon.social/tags/kidneys" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>kidneys</span></a>) are concerned are only partly (45%) explained by weight loss. What are we missing?</p>
Christos Argyropoulos MD, PhD, FASN 🇺🇸<p>We should talk about what hides under the clinical successes of <a class="hashtag" rel="nofollow noopener" href="https://bsky.app/search?q=%23glp1" target="_blank">#glp1</a> e.g. <a class="hashtag" rel="nofollow noopener" href="https://bsky.app/search?q=%23tirzepatide" target="_blank">#tirzepatide</a> or <a class="hashtag" rel="nofollow noopener" href="https://bsky.app/search?q=%23semaglutide" target="_blank">#semaglutide</a>. A paper published in the last 6 months suggests that the benefits (at least as the <a class="hashtag" rel="nofollow noopener" href="https://bsky.app/search?q=%23kidneys" target="_blank">#kidneys</a>) are concerned are only partly (45%) explained by weight loss. What are we missing?</p>
Martin Michaelis (he/him)<p><a href="https://mastodonapp.uk/tags/Evidence" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Evidence</span></a> that <a href="https://mastodonapp.uk/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> (<a href="https://mastodonapp.uk/tags/Munjaro" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Munjaro</span></a>) causes more pronounced <a href="https://mastodonapp.uk/tags/weightloss" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>weightloss</span></a> than <a href="https://mastodonapp.uk/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a> (<a href="https://mastodonapp.uk/tags/Wegovy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Wegovy</span></a>, <a href="https://mastodonapp.uk/tags/Ozempic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Ozempic</span></a>, <a href="https://mastodonapp.uk/tags/Rybelsus" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Rybelsus</span></a>). Notably, the trial was funded by the pharma company behind tirzepatide.</p><p><a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2416394" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nejm.org/doi/full/10.1056/NEJM</span><span class="invisible">oa2416394</span></a></p>
DrBob, Neurologist, 🧠Mechanic<p>New Review and Meta-Analysis confirms weight gain with discontinuance of <a href="https://vmst.io/tags/Semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Semaglutide</span></a> and <a href="https://vmst.io/tags/Tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Tirzepatide</span></a> </p><p>Discontinuing GLP1 medications led to a pooled overall mean weight regain of 9.69 kg (or about 22 lbs in patients prescribed semaglutide/tirzepatide. The proportion of weight regained was proportional to the amount originally lost.</p><p>Discontinuation of GLP-1RA treatment leads to weight regain, regardless of lifestyle interventions, and should therefore be considered a chronic therapy to prevent weight regain and associated undesirable outcomes related to <a href="https://vmst.io/tags/Obesity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Obesity</span></a>.</p><p><a href="https://vmst.io/tags/wegovy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>wegovy</span></a> <a href="https://vmst.io/tags/ozempic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ozempic</span></a> <a href="https://vmst.io/tags/mounjaro" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mounjaro</span></a> <a href="https://vmst.io/tags/zepbound" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>zepbound</span></a><br><a href="https://onlinelibrary.wiley.com/doi/10.1111/obr.13929" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">onlinelibrary.wiley.com/doi/10</span><span class="invisible">.1111/obr.13929</span></a></p>
Martin Michaelis (he/him)<p>GLP-1 receptor agonists may reduce the risk of haematological <a href="https://mastodonapp.uk/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancer</span></a> in patients with type 2 <a href="https://mastodonapp.uk/tags/diabetes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>diabetes</span></a>. <a href="https://mastodonapp.uk/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a> <a href="https://mastodonapp.uk/tags/liraglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>liraglutide</span></a> <a href="https://mastodonapp.uk/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> </p><p><a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2831083" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jamanetwork.com/journals/jaman</span><span class="invisible">etworkopen/fullarticle/2831083</span></a></p>
Preston Maness ☭<p><a href="https://tenforward.social/tags/Tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Tirzepatide</span></a> ad in the theater: one of the possible side effects listed as "inflamed pancreas." That feels like a scummy way to avoid saying <a href="https://tenforward.social/tags/pancreatitis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pancreatitis</span></a>. It's no fun. But it's a rare side-effect at least. I'm on <a href="https://tenforward.social/tags/dulaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>dulaglutide</span></a> which also has that as a rare side-effect. But I had already developed <a href="https://tenforward.social/tags/ChronicPancreatitis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ChronicPancreatitis</span></a> at that point, so, kinda water under the bridge for me at least.</p>
Simon Zerafa<p>Very interesting programme on BBC Panorama about the use of Tirzepatide for weight loss.</p><p><a href="https://infosec.exchange/tags/Tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Tirzepatide</span></a> <a href="https://infosec.exchange/tags/WeightLoss" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>WeightLoss</span></a></p>
DrBob, Neurologist, 🧠Mechanic<p>Good news re: GLP1 medications like <a href="https://vmst.io/tags/Zepbound" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Zepbound</span></a> (<a href="https://vmst.io/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a>) and <a href="https://vmst.io/tags/Wegovy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Wegovy</span></a> (<a href="https://vmst.io/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a>.)</p><p>Biden-⁠Harris Administration Takes Latest Step to Lower Prescription Drug Costs by Proposing Expanded Coverage of Anti-Obesity Medications for Americans with Medicare and Medicaid</p><p><a href="https://www.whitehouse.gov/briefing-room/statements-releases/2024/11/26/fact-sheet-biden-harris-administration-takes-latest-step-to-lower-prescription-drug-costs-by-proposing-expanded-coverage-of-anti-obesity-medications-for-americans-with-medicare-and-medicaid/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">whitehouse.gov/briefing-room/s</span><span class="invisible">tatements-releases/2024/11/26/fact-sheet-biden-harris-administration-takes-latest-step-to-lower-prescription-drug-costs-by-proposing-expanded-coverage-of-anti-obesity-medications-for-americans-with-medicare-and-medicaid/</span></a></p>
DrBob, Neurologist, 🧠Mechanic<p>Is this the FDA‘s backdoor to reduce the cost of drugs in America?</p><p>This opinion piece by Dr Scott Gottlieb, a Pfizer board member, may be biased towards the pharmaceutical industry 🤔</p><p>“<a href="https://vmst.io/tags/FDA" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FDA</span></a>’s permissive stance on the compounding of GLP-1 drugs used for weight loss. Initially, the agency cited shortages of <a href="https://vmst.io/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a> and <a href="https://vmst.io/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> — the active ingredients in the popular drugs <a href="https://vmst.io/tags/Wegovy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Wegovy</span></a> and <a href="https://vmst.io/tags/Zepbound" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Zepbound</span></a> — and allowed pharmacies to compound these drugs under a provision for addressing drug shortages.</p><p><a href="https://vmst.io/tags/obesity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>obesity</span></a> <a href="https://vmst.io/tags/glp1" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>glp1</span></a><br><a href="https://www.statnews.com/2024/11/19/fda-glp-1s-weight-loss-drugs-zepbound-wegovy-compounding-law/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">statnews.com/2024/11/19/fda-gl</span><span class="invisible">p-1s-weight-loss-drugs-zepbound-wegovy-compounding-law/</span></a></p>
DrBob, Neurologist, 🧠Mechanic<p><a href="https://vmst.io/tags/Obesity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Obesity</span></a> Drug Shows Promise in Easing Knee <a href="https://vmst.io/tags/Osteoarthritis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Osteoarthritis</span></a> Pain </p><p>As a practicing physician, I've seen up close the remarkable benefits of the <a href="https://vmst.io/tags/GLP1" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>GLP1</span></a> class of medications, including <a href="https://vmst.io/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a> (<a href="https://vmst.io/tags/Ozempic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Ozempic</span></a>, <a href="https://vmst.io/tags/Wegovy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Wegovy</span></a>) and <a href="https://vmst.io/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> (<a href="https://vmst.io/tags/Mounjaro" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Mounjaro</span></a>, <a href="https://vmst.io/tags/Zepbound" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Zepbound</span></a>.)</p><p>Reduction in weight (and inflammation) are game changers. </p><p>Better control of <a href="https://vmst.io/tags/Diabetes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Diabetes</span></a>, reduced <a href="https://vmst.io/tags/Cardiovascular" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cardiovascular</span></a> and <a href="https://vmst.io/tags/Stroke" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Stroke</span></a> risk, maybe lower incident of <a href="https://vmst.io/tags/Dementia" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Dementia</span></a>, <a href="https://vmst.io/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> and other diseases which have an 'inflammatory' component.</p><p>All we need now is to lower the cost (about $1,000/month in the US; heard the price is $59 in EU!)</p><p><a href="https://www.nytimes.com/2024/10/30/health/ozempic-wegovy-knee-pain-osteoarthritis.html" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nytimes.com/2024/10/30/health/</span><span class="invisible">ozempic-wegovy-knee-pain-osteoarthritis.html</span></a></p>
Martin KosteraProbíral jsem s kámošem ty moje levné náhražky Saxendy, Ozempicu a Mounjara. Poslal jsem mu tu svou "rešerši" a sepsul mě, že jsem neuvedl obyčejné kvasnice. Obyčejné droždí. Málem jsem se pozvracel. 🤮😂<br>A to prosím neznám osobně druhou osobu, která by droždí jedla, než moje mamka a vždy jsem prchal, abych to neviděl. 😁<br><br>Ale je to fakt. Je to extrémně levné. 42g(2g je ten hliníkový obal, bych řekl) balení stojí 5-12 kaček. Je z toho cca 20g čistého betaglukanu, což je skoro ta jedna pomyslná dávka, kterou simulují léky na hubnutí. Takže jedna krychlička denně.<br><br><span class="">#^</span><a class="" href="https://www.rohlik.cz/1289859-uniferm-drozdi-cerstve" rel="nofollow noopener" target="_blank">https://www.rohlik.cz/1289859-uniferm-drozdi-cerstve</a><br><span class="">#^</span><a class="" href="https://www.rohlik.cz/1305551-fala-pekarske-drozdi-cerstve" rel="nofollow noopener" target="_blank">https://www.rohlik.cz/1305551-fala-pekarske-drozdi-cerstve</a><br><br>Jako jo, jde to, ale já bych to do sebe nedostal ani párem volů. To raději chroupat půl kila ovsa denně... 🐎<br><br>Více viz:<br><span class="">#^</span><a class="" href="https://libera.site/item/a55497fa-97b2-4172-8105-2a7b91c7bd5c" rel="nofollow noopener" target="_blank">https://libera.site/item/a55497fa-97b2-4172-8105-2a7b91c7bd5c</a><br><br>#<a class="" href="https://libera.site/search?tag=Betaglukan" rel="nofollow noopener" target="_blank">Betaglukan</a> #<a class="" href="https://libera.site/search?tag=Ozempic" rel="nofollow noopener" target="_blank">Ozempic</a> #<a class="" href="https://libera.site/search?tag=Saxenda" rel="nofollow noopener" target="_blank">Saxenda</a> #<a class="" href="https://libera.site/search?tag=Mounjaro" rel="nofollow noopener" target="_blank">Mounjaro</a> #<a class="" href="https://libera.site/search?tag=Semaglutide" rel="nofollow noopener" target="_blank">Semaglutide</a> #<a class="" href="https://libera.site/search?tag=Liraglutide" rel="nofollow noopener" target="_blank">Liraglutide</a> #<a class="" href="https://libera.site/search?tag=Tirzepatide" rel="nofollow noopener" target="_blank">Tirzepatide</a> #<a class="" href="https://libera.site/search?tag=Kvasnice" rel="nofollow noopener" target="_blank">Kvasnice</a> #<a class="" href="https://libera.site/search?tag=Dro%C5%BEd%C3%AD" rel="nofollow noopener" target="_blank">Droždí</a>
🇨🇦A Wolf in Cheap Clothing🇨🇦<p><a href="https://www.cnn.com/2024/08/20/health/tirzepatide-diabetes-lilly-trial/index.html" rel="nofollow noopener" target="_blank">https://www.cnn.com/2024/08/20/health/tirzepatide-diabetes-lilly-trial/index.html</a><span><br><br></span><a href="https://calckey.world/tags/Tirzepatide" rel="nofollow noopener" target="_blank">#Tirzepatide</a><span> cuts risk of </span><a href="https://calckey.world/tags/diabetes" rel="nofollow noopener" target="_blank">#diabetes</a><span> by 94% in adults with </span><a href="https://calckey.world/tags/prediabetes" rel="nofollow noopener" target="_blank">#prediabetes</a><span> and </span><a href="https://calckey.world/tags/obesity" rel="nofollow noopener" target="_blank">#obesity</a><span> or </span><a href="https://calckey.world/tags/overweight" rel="nofollow noopener" target="_blank">#overweight</a><span>, drugmaker says</span></p>
Jason H. Moore, Ph.D.<p>GLP-1 physiology in obesity and development of incretin-based drugs for chronic weight management <a href="https://www.nature.com/articles/s42255-024-01113-9" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s42255-024</span><span class="invisible">-01113-9</span></a> <a href="https://mastodon.online/tags/glp1" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>glp1</span></a> <a href="https://mastodon.online/tags/semaglutide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>semaglutide</span></a> <a href="https://mastodon.online/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> <a href="https://mastodon.online/tags/obesity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>obesity</span></a> <a href="https://mastodon.online/tags/diabetes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>diabetes</span></a> <a href="https://mastodon.online/tags/weightloss" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>weightloss</span></a></p>
Digital Human ✔<p>De risico's van snelle gewichtsverlies medicatie onthuld <a href="https://www.trendingtech.news/trending-news/2024/08/26897/de-risico-s-van-snelle-gewichtsverlies-medicatie-onthuld" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">trendingtech.news/trending-new</span><span class="invisible">s/2024/08/26897/de-risico-s-van-snelle-gewichtsverlies-medicatie-onthuld</span></a> <a href="https://mastodon.social/tags/gewichtsverlies" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>gewichtsverlies</span></a> medicatie <a href="https://mastodon.social/tags/tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tirzepatide</span></a> <a href="https://mastodon.social/tags/thyrotoxicosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thyrotoxicosis</span></a> <a href="https://mastodon.social/tags/dosisaanpassing" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>dosisaanpassing</span></a> <a href="https://mastodon.social/tags/atriale" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>atriale</span></a> fibrillatie <a href="https://mastodon.social/tags/Trending" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Trending</span></a> <a href="https://mastodon.social/tags/News" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>News</span></a> <a href="https://mastodon.social/tags/Nieuws" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Nieuws</span></a></p>
Martin KosteraTak jsem si udělal menší rešerši.<br><br>Podle <span class="">#^</span><a class="" href="https://www.sciencealert.com/one-type-of-fiber-could-have-weight-loss-benefits-similar-to-ozempic" rel="nofollow noopener" target="_blank">https://www.sciencealert.com/one-type-of-fiber-could-have-weight-loss-benefits-similar-to-ozempic</a><br>by člověk měl do sebe dostat cca 25-30g betaglukanu denně. Ty jsou v kvasnicích, houbách a ovsi.<br><br><strong>Extrakt z ovse</strong><br><span class="">#^</span><a class="" href="https://www.pangamin.cz/cardio-well-300g-50g-zdarma_z1540/" rel="nofollow noopener" target="_blank">https://www.pangamin.cz/cardio-well-300g-50g-zdarma_z1540/</a><br>40g denně, tedy balení je na cca 10 dnů. Denní dávka stojí cca 40Kč.<br><br><strong>Kvasnice</strong><br><span class="">#^</span><a class="" href="https://www.pangamin.cz/pangamin-klasik-sacek_z9/" rel="nofollow noopener" target="_blank">https://www.pangamin.cz/pangamin-klasik-sacek_z9/</a><br>Cca půlka hmotnosti buňky je betaglukan, takže balení s 90g stačí na cca 2 dny. Denní dávka stojí cca 45Kč.<br>(hrozně mi to páchne a nedělají to v tobolkách)<br><br><strong>Oves</strong><br>Betaglukanů je v ovsi cca 3-6% hmotnosti. Tzn. 0,5-1kg ovsa denně. 🐎🐴😱<br><br>Takže nic moc. Nic koncentrovanějšího jsem zatím nenašel.<br>Chtělo by to čistý betaglukan. Kdyby někdo měl chuť na startup. To je očividná díra na trhu...<br><br><br>#<a class="" href="https://libera.site/search?tag=Betaglukan" rel="nofollow noopener" target="_blank">Betaglukan</a> #<a class="" href="https://libera.site/search?tag=Ozempic" rel="nofollow noopener" target="_blank">Ozempic</a> #<a class="" href="https://libera.site/search?tag=Saxenda" rel="nofollow noopener" target="_blank">Saxenda</a> #<a class="" href="https://libera.site/search?tag=Mounjaro" rel="nofollow noopener" target="_blank">Mounjaro</a> #<a class="" href="https://libera.site/search?tag=Semaglutide" rel="nofollow noopener" target="_blank">Semaglutide</a> #<a class="" href="https://libera.site/search?tag=Liraglutide" rel="nofollow noopener" target="_blank">Liraglutide</a> #<a class="" href="https://libera.site/search?tag=Tirzepatide" rel="nofollow noopener" target="_blank">Tirzepatide</a>
Martin KosteraBetaglukan se nejlépe zpracovává a produkuje butyrát. Butyrát spouští produkci GLP-1. GLP-1(a jejich syntetické analogy Saxenda, Ozempic, Mounjaro ...) regulují příjem potravy, cukrovku a tak...<br><br>Papejte betaglukan!<br><br>A teď mě omluvte, jdu si udělat do online lékáren rešerši...<br><br> <a href="https://flipboard.com/@ScienceAlert" rel="nofollow noopener" target="_blank"></a><span><a href="https://flipboard.com/@ScienceAlert" rel="nofollow noopener" target="_blank">ScienceAlert</a> wrote the following <a href="https://flipboard.com/@sciencealert/sciencealert-3mvdqjtaz/-/a-4lK23N0PTTSicy0mbbVvqA%3Aa%3A565656366-%2F0" rel="nofollow noopener" target="_blank">post</a> <span class="">Wed, 24 Jul 2024 05:53:36 +0200</span></span> One Type of Fiber Could Have Weight Loss Benefits Similar to Ozempic<br><a href="https://www.sciencealert.com/one-type-of-fiber-could-have-weight-loss-benefits-similar-to-ozempic?utm_source=flipboard&amp;utm_medium=activitypub" rel="nofollow noopener" target="_blank">https://www.sciencealert.com/one-type-of-fiber-could-have-weight-loss-benefits-similar-to-ozempic?utm_source=flipboard&amp;utm_medium=activitypub </a><br><br>Posted into ScienceAlert <a href="https://flipboard.com/@sciencealert/sciencealert-3mvdqjtaz" rel="nofollow noopener" target="_blank">@sciencealert-ScienceAlert</a> <br><br>#<a class="" href="https://libera.site/search?tag=Betaglukan" rel="nofollow noopener" target="_blank">Betaglukan</a> #<a class="" href="https://libera.site/search?tag=Ozempic" rel="nofollow noopener" target="_blank">Ozempic</a> #<a class="" href="https://libera.site/search?tag=Saxenda" rel="nofollow noopener" target="_blank">Saxenda</a> #<a class="" href="https://libera.site/search?tag=Mounjaro" rel="nofollow noopener" target="_blank">Mounjaro</a> #<a class="" href="https://libera.site/search?tag=Semaglutide" rel="nofollow noopener" target="_blank">Semaglutide</a> #<a class="" href="https://libera.site/search?tag=Liraglutide" rel="nofollow noopener" target="_blank">Liraglutide</a> #<a class="" href="https://libera.site/search?tag=Tirzepatide" rel="nofollow noopener" target="_blank">Tirzepatide</a>
CDCastillo<p>La tirzepatida (medicamento para tratar la <a href="https://mastodon.cloud/tags/Diabetes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Diabetes</span></a> ) disminuyó un 35% la probabilidad de desarrollar <a href="https://mastodon.cloud/tags/Neuropat%C3%ADaDiab%C3%A9tica" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>NeuropatíaDiabética</span></a> (de 4.8% a 3%) a lo largo de 2 años. Otros agonistas de receptor <a href="https://mastodon.cloud/tags/GLP1" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>GLP1</span></a> parecen tener efecto similar.</p><p>Probablemente también ayude a regenerar neuronas del SNC (hipocampo, substantia nigra, etc): en modelos animales tuvo efecto protector contra <a href="https://mastodon.cloud/tags/Parkinson" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Parkinson</span></a> y <a href="https://mastodon.cloud/tags/Alzheimer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Alzheimer</span></a></p><p><a href="https://pubmed.ncbi.nlm.nih.gov/34455311/" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/344553</span><span class="invisible">11/</span></a></p><p><a href="https://mastodon.cloud/tags/Tirzepatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Tirzepatide</span></a> <a href="https://mastodon.cloud/tags/Exenatide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Exenatide</span></a> <a href="https://mastodon.cloud/tags/PeripheralNerveSociety" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PeripheralNerveSociety</span></a> <a href="https://mastodon.cloud/tags/AnualMeeting" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AnualMeeting</span></a> #2024</p>