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#SPINA_GT

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SPINA Team<p>Growing evidence supports a role of sensorimotor and autonomic <a href="https://fosstodon.org/tags/neuropathy" class="mention hashtag" rel="tag">#<span>neuropathy</span></a> in <a href="https://fosstodon.org/tags/syndrome_T" class="mention hashtag" rel="tag">#<span>syndrome_T</span></a> or <a href="https://fosstodon.org/tags/SORSHOT" class="mention hashtag" rel="tag">#<span>SORSHOT</span></a>, i.e. reduced quality of life in treated <a href="https://fosstodon.org/tags/hypothyroidism" class="mention hashtag" rel="tag">#<span>hypothyroidism</span></a>. <a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a> and <a href="https://fosstodon.org/tags/SPINA_GD" class="mention hashtag" rel="tag">#<span>SPINA_GD</span></a> predict nerve function and depression.</p><p><a href="https://pubmed.ncbi.nlm.nih.gov/38811750/" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/388117</span><span class="invisible">50/</span></a></p><p><a href="https://doi.org/10.1038/s41598-024-63158-w" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1038/s41598-024-631</span><span class="invisible">58-w</span></a></p>
SPINA Team<p>Again, a study showed a strong influence of endocrine disruptors on <a href="https://fosstodon.org/tags/thyroid" class="mention hashtag" rel="tag">#<span>thyroid</span></a> homeostasis. Exposure to butylparaben significantly reduces <a href="https://fosstodon.org/tags/SPINA" class="mention hashtag" rel="tag">#<span>SPINA</span></a>-GD, whereas ethylparaben slightly increases <a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a> in pregnancy.</p><p><a href="https://pubmed.ncbi.nlm.nih.gov/39889471/" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/398894</span><span class="invisible">71/</span></a></p><p><a href="https://doi.org/10.1016/j.ecoenv.2025.117818" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1016/j.ecoenv.2025.</span><span class="invisible">117818</span></a></p>
Johannes W. Dietrich<p>Should we, therefore, classify <a href="https://qoto.org/tags/syndrome_T" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>syndrome_T</span></a> as a psychosomatic disease? This would be premature and probably wrong. We found signs of sensorimotor and autonomic <a href="https://qoto.org/tags/neuropathy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>neuropathy</span></a> that depend on autoimmunity and <a href="https://qoto.org/tags/thyroid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>thyroid</span></a>'s secretory capacity (<a href="https://qoto.org/tags/SPINA_GT" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SPINA_GT</span></a>).</p>
SPINA Team<p><a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a>, <a href="https://fosstodon.org/tags/SPINA_GD" class="mention hashtag" rel="tag">#<span>SPINA_GD</span></a> and Jostel&#39;s TSH index (<a href="https://fosstodon.org/tags/JTI" class="mention hashtag" rel="tag">#<span>JTI</span></a> or <a href="https://fosstodon.org/tags/TSHI" class="mention hashtag" rel="tag">#<span>TSHI</span></a>) are predictors of survival in patients with <a href="https://fosstodon.org/tags/Takotsubo" class="mention hashtag" rel="tag">#<span>Takotsubo</span></a> syndrome (<a href="https://fosstodon.org/tags/stress" class="mention hashtag" rel="tag">#<span>stress</span></a> <a href="https://fosstodon.org/tags/cardiomyopathy" class="mention hashtag" rel="tag">#<span>cardiomyopathy</span></a>), as recently demonstrated in the international GEIST registry.</p><p><a href="https://pubmed.ncbi.nlm.nih.gov/38502972/" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/385029</span><span class="invisible">72/</span></a><br /><a href="https://doi.org/10.1016/j.ebiom.2024.105063" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1016/j.ebiom.2024.1</span><span class="invisible">05063</span></a></p>
SPINA Team<p><a href="https://fosstodon.org/tags/SPINA_GD" class="mention hashtag" rel="tag">#<span>SPINA_GD</span></a> is reduced in major <a href="https://fosstodon.org/tags/depression" class="mention hashtag" rel="tag">#<span>depression</span></a>, <a href="https://fosstodon.org/tags/bipolar" class="mention hashtag" rel="tag">#<span>bipolar</span></a> disorder and <a href="https://fosstodon.org/tags/schizophrenia" class="mention hashtag" rel="tag">#<span>schizophrenia</span></a>, whereas <a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a> is elevated in schizophrenia and bipolar disorder, marking a unique profile of <a href="https://fosstodon.org/tags/thyroid_allostasis" class="mention hashtag" rel="tag">#<span>thyroid_allostasis</span></a>. <a href="https://pubmed.ncbi.nlm.nih.gov/38277991/" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/382779</span><span class="invisible">91/</span></a> <a href="https://doi.org/10.1016/j.psyneuen.2024.106962" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1016/j.psyneuen.202</span><span class="invisible">4.106962</span></a></p>
SPINA Team<p><a href="https://fosstodon.org/tags/Metformin" class="mention hashtag" rel="tag">#<span>Metformin</span></a> is known to reduce <a href="https://fosstodon.org/tags/TSH" class="mention hashtag" rel="tag">#<span>TSH</span></a> concentration, but it was unknown if this effect reflects central action or improved thyroid function. A recent study shows that <a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a> rises in women with autoimmune thyroiditis under treatment with metformin. <a href="https://pubmed.ncbi.nlm.nih.gov/38051473/" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/380514</span><span class="invisible">73/</span></a></p>
SPINA Team<p><a href="https://fosstodon.org/tags/SPINA_Thyr" class="mention hashtag" rel="tag">#<span>SPINA_Thyr</span></a> may be useful for monitoring of <a href="https://fosstodon.org/tags/endocrine" class="mention hashtag" rel="tag">#<span>endocrine</span></a> disruptors. <a href="https://fosstodon.org/tags/SPINA_GD" class="mention hashtag" rel="tag">#<span>SPINA_GD</span></a> correlates to paraben excretion, and <a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a> is modified due to exposure to butylparaben. <a href="https://doi.org/10.1007/s11356-023-31277-y" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1007/s11356-023-312</span><span class="invisible">77-y</span></a> <a href="https://pubmed.ncbi.nlm.nih.gov/38038926/" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/380389</span><span class="invisible">26/</span></a></p>
Johannes W. Dietrich<p><a href="https://qoto.org/tags/Thyroid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Thyroid</span></a>'s secretory (<a href="https://qoto.org/tags/SPINA_GT" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>SPINA_GT</span></a>) is higher in borderline personality disorder (<a href="https://qoto.org/tags/BPD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BPD</span></a>) compared to controls. Is this a result of dynamical compensation or from sympathetic innervation of the thyroid gland? <a href="https://doi.org/10.3390/jcm12216702" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="">doi.org/10.3390/jcm12216702</span><span class="invisible"></span></a></p>
SPINA Team<p><a href="https://fosstodon.org/tags/Nickel" class="mention hashtag" rel="tag">#<span>Nickel</span></a> is a toxic metal and an important endocrine disruptor. Recent research shows that exposure to nickel impairs <a href="https://fosstodon.org/tags/thyroid" class="mention hashtag" rel="tag">#<span>thyroid</span></a>&#39;s secretory capacity (<a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a>). <a href="https://pubmed.ncbi.nlm.nih.gov/37800147/" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/378001</span><span class="invisible">47/</span></a> <a href="https://doi.org/10.3389/fendo.2023.1145153" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.3389/fendo.2023.114</span><span class="invisible">5153</span></a></p>
SPINA Team<p>Both <a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a> and <a href="https://fosstodon.org/tags/SPINA_GD" class="mention hashtag" rel="tag">#<span>SPINA_GD</span></a> are reduced in myalgic encephalomyelitis / chronic fatigue syndrome (<a href="https://fosstodon.org/tags/MECFS" class="mention hashtag" rel="tag">#<span>MECFS</span></a>). SPINA-GD is especially low in persons with antibodies to selenoprotein P, suggesting a pivotal role of selenium in ME/CFS. <a href="https://pubmed.ncbi.nlm.nih.gov/37423160/" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/374231</span><span class="invisible">60/</span></a> <a href="https://doi.org/10.1016/j.redox.2023.102796" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1016/j.redox.2023.1</span><span class="invisible">02796</span></a></p>
SPINA Team<p>In a prospective study including women with <a href="https://fosstodon.org/tags/euthyroid" class="mention hashtag" rel="tag">#<span>euthyroid</span></a> autoimmune <a href="https://fosstodon.org/tags/thyroiditis" class="mention hashtag" rel="tag">#<span>thyroiditis</span></a> treatment with <a href="https://fosstodon.org/tags/vitamin_D" class="mention hashtag" rel="tag">#<span>vitamin_D</span></a> increased <a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a>, and therapy with selenomethionine raised <a href="https://fosstodon.org/tags/SPINA_GD" class="mention hashtag" rel="tag">#<span>SPINA_GD</span></a>, in parallel to improved <a href="https://fosstodon.org/tags/sexual" class="mention hashtag" rel="tag">#<span>sexual</span></a> function and reduced <a href="https://fosstodon.org/tags/depressive" class="mention hashtag" rel="tag">#<span>depressive</span></a> symptoms. <a href="https://doi.org/10.3390/nu15122815" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="">doi.org/10.3390/nu15122815</span><span class="invisible"></span></a></p>
SPINA Team<p>Both <a href="https://fosstodon.org/tags/SPINA_GT" class="mention hashtag" rel="tag">#<span>SPINA_GT</span></a> and <a href="https://fosstodon.org/tags/SPINA_GD" class="mention hashtag" rel="tag">#<span>SPINA_GD</span></a> correlate with multiple <a href="https://fosstodon.org/tags/biomarker" class="mention hashtag" rel="tag">#<span>biomarker</span></a>​s for <a href="https://fosstodon.org/tags/cardiovascular_risk" class="mention hashtag" rel="tag">#<span>cardiovascular_risk</span></a>. <br /><a href="https://pubmed.ncbi.nlm.nih.gov/36680358/" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">pubmed.ncbi.nlm.nih.gov/366803</span><span class="invisible">58/</span></a> <a href="https://doi.org/10.1177/10815589221149187" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1177/10815589221149</span><span class="invisible">187</span></a></p>
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