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Karl Theodor<p>J Nat Prod. 2022 Jan 28;85(1):176-184. doi: 10.1021/acs.jnatprod.1c00946. Epub 2022 Jan 10.</p><p>+++ <a href="https://mastodon.social/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> +++</p><p>Block Cellular Entry of SARS-CoV-2 and the Emerging Variants</p><p>Richard B van Breemen 1, Ruth N Muchiri 1, Timothy A Bates 2, Jules B Weinstein 2, Hans C Leier 2, Scotland Farley 2, Fikadu G Tafesse 2<br>Affiliations Expand<br>PMID: 35007072 PMCID: PMC8768006 DOI: 10.1021/acs.jnatprod.1c00946 </p><p><a href="https://mastodon.social/tags/Corona" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Corona</span></a> <a href="https://mastodon.social/tags/Cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabis</span></a> <a href="https://mastodon.social/tags/Cannabinoide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoide</span></a> <a href="https://mastodon.social/tags/Endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Endocannabinoidsystem</span></a> des Menschen [<a href="https://mastodon.social/tags/ECS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ECS</span></a>] <a href="https://mastodon.social/tags/WEEDMoB" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>WEEDMoB</span></a> <a href="https://mastodon.social/tags/Streeck" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Streeck</span></a></p>
jnpn<p>jnpn 2025 et cannabis <a href="https://www.youtube.com/watch?v=l8ZKcmoaltE" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="">youtube.com/watch?v=l8ZKcmoaltE</span><span class="invisible"></span></a></p><p><a href="https://mastodon.social/tags/neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurology</span></a> <a href="https://mastodon.social/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a></p>
Karl Theodor<p>J Nat Prod. 2022 Jan 28;85(1):176-184. doi: 10.1021/acs.jnatprod.1c00946. Epub 2022 Jan 10.</p><p>+++ <a href="https://mastodon.social/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> +++</p><p>Block Cellular Entry of SARS-CoV-2 and the Emerging Variants</p><p>Richard B van Breemen 1, Ruth N Muchiri 1, Timothy A Bates 2, Jules B Weinstein 2, Hans C Leier 2, Scotland Farley 2, Fikadu G Tafesse 2<br>Affiliations Expand<br>PMID: 35007072 PMCID: PMC8768006 DOI: 10.1021/acs.jnatprod.1c00946 </p><p><a href="https://mastodon.social/tags/Corona" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Corona</span></a> <a href="https://mastodon.social/tags/Cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabis</span></a> <a href="https://mastodon.social/tags/Cannabinoide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoide</span></a> <a href="https://mastodon.social/tags/Endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Endocannabinoidsystem</span></a> des Menschen [<a href="https://mastodon.social/tags/ECS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ECS</span></a>] <a href="https://mastodon.social/tags/WEEDMoB" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>WEEDMoB</span></a> <a href="https://mastodon.social/tags/Streeck" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Streeck</span></a></p>
JADe (he, him)<p>A farewell to Pepe Mujica, who recently passed away and really led by example ( ESPAÑOL MÁS ABAJO)</p><p>ENG: "He established an agenda of rights that marked his administration by fire; he promoted the 8-hour working day for rural workers when he was Minister of Livestock, and during his term of office, the day of the rural worker was declared, which is celebrated every 30 April; The law on the voluntary interruption of pregnancy (with the main rationale of accompanying women in their decision and not as a mere act of ending a life); the regulation of marijuana consumption, which put Uruguay in the international spotlight as a testing ground for the legalisation of all drugs in order to put an end to a war that only leaves deaths along the way."</p><p>ESP: "Consagró una agenda de derechos que marcaron a fuego su gestión; promovió las 8 horas para el trabajador rural siendo ministro de Ganadería, y durante su mandato se declaró el día del peón rural que se celebra cada 30 de abril; el matrimonio igualitario, la ley de interrupción voluntaria del embarazo (con la fundamentación principal de acompañar a las mujeres en la decisión y no como un mero acto de poner fin a una vida); la regulación del consumo de marihuana, con la que puso al Uruguay en la mira internacional como un campo de prueba hacia la legalización de todas las drogas para poner fin a una guerra que solo deja muertos por el camino."</p><p><a href="https://otromundoinfo.wordpress.com/2025/05/14/naides-es-mas-que-naides/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">otromundoinfo.wordpress.com/20</span><span class="invisible">25/05/14/naides-es-mas-que-naides/</span></a></p><p><a href="https://mastodon.cr/tags/pepemujica" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pepemujica</span></a> <a href="https://mastodon.cr/tags/pepe_mujica" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pepe_mujica</span></a> <br><a href="https://mastodon.cr/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a> <a href="https://mastodon.cr/tags/cannabismedicinal" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabismedicinal</span></a> <a href="https://mastodon.cr/tags/cannabislegalisierung" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabislegalisierung</span></a> <a href="https://mastodon.cr/tags/legaliza" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>legaliza</span></a><br><a href="https://mastodon.cr/tags/legalization" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>legalization</span></a> <a href="https://mastodon.cr/tags/cannabinoide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoide</span></a> <a href="https://mastodon.cr/tags/thc" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thc</span></a> <a href="https://mastodon.cr/tags/cbd" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbd</span></a> <a href="https://mastodon.cr/tags/cbn" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbn</span></a> <a href="https://mastodon.cr/tags/thca" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thca</span></a> <a href="https://mastodon.cr/tags/maconha" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>maconha</span></a> <a href="https://mastodon.cr/tags/marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuana</span></a> <a href="https://mastodon.cr/tags/marihuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marihuana</span></a> <a href="https://mastodon.cr/tags/PatientCare" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PatientCare</span></a> <a href="https://mastodon.cr/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> <a href="https://mastodon.cr/tags/Endocannabinoide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Endocannabinoide</span></a> <a href="https://mastodon.cr/tags/EfectoS%C3%A9quito" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>EfectoSéquito</span></a> <a href="https://mastodon.cr/tags/entourageeffect" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>entourageeffect</span></a></p>
JADe (he, him)<p>ENG: "Over 70% Of Studies Back Medical Cannabis In Cancer Treatment, Meta-Analysis Finds." They searched 10.000 published papers. Keep that in mind, next time you read the old " more reasearch is needed".</p><p>Will gladly share a proven protocol in comments if requested. Nothing for sale. Strictly educational purposes to correct such rampant intentional misinformation. </p><p><a href="https://www.forbes.com/sites/dariosabaghi/2025/04/21/over-70-of-studies-back-medical-cannabis-in-cancer-treatment-meta-analysis-finds/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">forbes.com/sites/dariosabaghi/</span><span class="invisible">2025/04/21/over-70-of-studies-back-medical-cannabis-in-cancer-treatment-meta-analysis-finds/</span></a></p><p>ESP: "Meta análisis de 10.000 estudios científicos publicados reveló una tendencia significativa ( 71.4%) que apoya el potencial terapéutico del cannabis, en particular para el manejo de los síntomas relacionados con el cáncer y efectos anticancerígenos directos." </p><p>Con gusto aclaro dudas sobre cómo usarlo para este fin. Solo pregunten en comentarios. No se vende nada, el fin es educativo para contrarrestar tanta desinformación intencional. </p><p>Enlace autotraducido:<br><a href="https://www-forbes-com.translate.goog/sites/dariosabaghi/2025/04/21/over-70-of-studies-back-medical-cannabis-in-cancer-treatment-meta-analysis-finds/?_x_tr_sl=auto&amp;_x_tr_tl=es&amp;_x_tr_hl=es-419&amp;_x_tr_pto=wapp&amp;_x_tr_hist=true" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">www-forbes-com.translate.goog/</span><span class="invisible">sites/dariosabaghi/2025/04/21/over-70-of-studies-back-medical-cannabis-in-cancer-treatment-meta-analysis-finds/?_x_tr_sl=auto&amp;_x_tr_tl=es&amp;_x_tr_hl=es-419&amp;_x_tr_pto=wapp&amp;_x_tr_hist=true</span></a></p><p><a href="https://mastodon.cr/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancer</span></a> <a href="https://mastodon.cr/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> <a href="https://mastodon.cr/tags/medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicine</span></a><br><a href="https://mastodon.cr/tags/marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuana</span></a> <a href="https://mastodon.cr/tags/cannabismedicinal" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabismedicinal</span></a><br><a href="https://mastodon.cr/tags/medicalcannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicalcannabis</span></a> <a href="https://mastodon.cr/tags/healing" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healing</span></a> <a href="https://mastodon.cr/tags/cbda" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbda</span></a> <a href="https://mastodon.cr/tags/chemotherapy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chemotherapy</span></a> <a href="https://mastodon.cr/tags/cbd" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbd</span></a> <a href="https://mastodon.cr/tags/quimioterapia" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>quimioterapia</span></a><br><a href="https://mastodon.cr/tags/thc" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thc</span></a> <a href="https://mastodon.cr/tags/thca" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thca</span></a> <a href="https://mastodon.cr/tags/regenerativemedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>regenerativemedicine</span></a><br><a href="https://mastodon.cr/tags/herbalist" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>herbalist</span></a> <a href="https://mastodon.cr/tags/healthare" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healthare</span></a> <a href="https://mastodon.cr/tags/healthscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healthscience</span></a><br><a href="https://mastodon.cr/tags/medical" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medical</span></a> <a href="https://mastodon.cr/tags/marijuananews" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuananews</span></a> <a href="https://mastodon.cr/tags/cbn" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbn</span></a> <a href="https://mastodon.cr/tags/homeostasis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>homeostasis</span></a> <a href="https://mastodon.cr/tags/chemo" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chemo</span></a> <a href="https://mastodon.cr/tags/pharmagreed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pharmagreed</span></a> <br><a href="https://mastodon.cr/tags/endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoidsystem</span></a> <a href="https://mastodon.cr/tags/weed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>weed</span></a><br><a href="https://mastodon.cr/tags/endocannabinoide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoide</span></a> <a href="https://mastodon.cr/tags/marihuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marihuana</span></a><br><a href="https://mastodon.cr/tags/pharma" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pharma</span></a> <a href="https://mastodon.cr/tags/pharmaceuticals" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pharmaceuticals</span></a> <a href="https://mastodon.cr/tags/healthcare" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healthcare</span></a> <a href="https://mastodon.cr/tags/HealthCrisis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>HealthCrisis</span></a> <a href="https://mastodon.cr/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>health</span></a></p><p>Edited for hashtags</p>
JADe (he, him)<p><a href="https://youtube.com/shorts/mi7cS5z2cJY?feature=shared" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">youtube.com/shorts/mi7cS5z2cJY</span><span class="invisible">?feature=shared</span></a></p><p>ENG: Observational study on medical <a href="https://mastodon.cr/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a> use for 300 people over 50 proves medical <a href="https://mastodon.cr/tags/weed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>weed</span></a> effectiveness. Patients favor high CBD low THC oral dosing ( balanced 1:1), to reduce arthritic/chronic pain and help sleep without having to chain smoke/vape. If CBD dominantes there is almost no psychotropic effect. </p><p>ESP: Ciencia moderna confirma que <a href="https://mastodon.cr/tags/marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuana</span></a> medicinal alivia dolor crónico, artrítis y sueño. Estudio con 300 personas de más de 50 años revela que pacientes prefieren gotas o comestibles altos en CBD y bajos en THC. Extracto 1:1 de flor resulta aún más efectivo y evita tener que fumar/vapear para sostener efectos analgésicos/ansiolíticos. De dominar el CBD el efecto psicotropico es nulo o mínimo. </p><p><a href="https://mastodon.cr/tags/memercredi" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>memercredi</span></a> <a href="https://mastodon.cr/tags/viernesdememes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>viernesdememes</span></a> <a href="https://mastodon.cr/tags/humour" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>humour</span></a> <a href="https://mastodon.cr/tags/funny" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>funny</span></a> <a href="https://mastodon.cr/tags/humor" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>humor</span></a> <a href="https://mastodon.cr/tags/salud" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>salud</span></a> <a href="https://mastodon.cr/tags/regenerativemedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>regenerativemedicine</span></a> <a href="https://mastodon.cr/tags/humornegro" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>humornegro</span></a><br><a href="https://mastodon.cr/tags/HumourNoir" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>HumourNoir</span></a> <a href="https://mastodon.cr/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://mastodon.cr/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>health</span></a><br><a href="https://mastodon.cr/tags/chronicillness" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chronicillness</span></a> <a href="https://mastodon.cr/tags/ChronicPainMemes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ChronicPainMemes</span></a><br><a href="https://mastodon.cr/tags/chronicpain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chronicpain</span></a> <a href="https://mastodon.cr/tags/thc" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thc</span></a> <a href="https://mastodon.cr/tags/cbd" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbd</span></a> <a href="https://mastodon.cr/tags/cbn" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbn</span></a> <a href="https://mastodon.cr/tags/thca" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thca</span></a><br><a href="https://mastodon.cr/tags/sleep" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>sleep</span></a> <a href="https://mastodon.cr/tags/arthritis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>arthritis</span></a> <a href="https://mastodon.cr/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a><br><a href="https://mastodon.cr/tags/cannabismedicinal" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabismedicinal</span></a> <a href="https://mastodon.cr/tags/cannabismedical" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabismedical</span></a> </p><p>ALT-TXT: Monochrome photo of old indigenous woman holding a huge joint between her swollen fingers. Text: SIGNS OF AGING: Swollen Joints</p>
Anna<p>Also: Does anyone know where to get <a href="https://aus.social/tags/CBN" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CBN</span></a> gummies an oils (not CBN in small quantities, isolate not great need small quantities of other <a href="https://aus.social/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a> &amp; <a href="https://aus.social/tags/terpenes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>terpenes</span></a> for entourage effect). Compounding only used isolates and even more expensive than real <a href="https://aus.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a>.</p><p>Also plain <a href="https://aus.social/tags/THC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>THC</span></a> <a href="https://aus.social/tags/gummies" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>gummies</span></a> or oil.</p><p>I need to mix &amp; match depending on day and needs.</p><p>In <a href="https://aus.social/tags/Australia" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Australia</span></a> &amp; have permit. Can no long get it from overseas. All the suppliers I used were threatened by Australian government but meds I need are super expensive or unavailable in Australia. I’m stuck.</p><p>I tried vaping. It burned my lungs and throat and aches for a week. Also took me on extremely bad trip.I didn’t get much sleep so vaping isn’t for me. Non-smoker too. I’m trying not to wreck organs still working.</p><p>Help appreciated. Let me know if should post this elsewhere for better input. Very energy limited.</p><p><span class="h-card" translate="no"><a href="https://a.gup.pe/u/chronicpain" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>chronicpain</span></a></span> <span class="h-card" translate="no"><a href="https://a.gup.pe/u/chronicillness" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>chronicillness</span></a></span></p>
Karl Theodor<p><span class="h-card" translate="no"><a href="https://thecannaclub.social/@verdantsquare" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>verdantsquare</span></a></span> ask him please 😎 </p><p><a href="https://mastodon.social/tags/Neurobiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurobiology</span></a> and <a href="https://mastodon.social/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a><br>This episode is about <a href="https://mastodon.social/tags/neurobiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurobiology</span></a> and cannabinoids, the compounds in <a href="https://mastodon.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a>. We talk to Dr. <a href="https://mastodon.social/tags/DanielePiomelli" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DanielePiomelli</span></a>, a neurobiology professor at UC Irvine, and Dr. <a href="https://mastodon.social/tags/FranjoGrotenhermen" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FranjoGrotenhermen</span></a>, a cannabis physician and researcher.</p><p>We learn how cannabinoids affect the <a href="https://mastodon.social/tags/brain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>brain</span></a>'s <a href="https://mastodon.social/tags/endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoidsystem</span></a>, which controls many functions and <a href="https://mastodon.social/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>health</span></a>. </p><p>Join us to find out the latest facts and debates in this exciting field. <a href="https://cannabis-med.org/de/cannabis-talk" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">cannabis-med.org/de/cannabis-t</span><span class="invisible">alk</span></a></p>
JADe (he, him)<p>"The <a href="https://mastodon.cr/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a> plant contains hundreds of chemical compounds. Among them <a href="https://mastodon.cr/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> , <a href="https://mastodon.cr/tags/flavonoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>flavonoids</span></a> and <a href="https://mastodon.cr/tags/terpenes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>terpenes</span></a> are the most relevant. Delta-nine <a href="https://mastodon.cr/tags/THC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>THC</span></a> and <a href="https://mastodon.cr/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CBD</span></a> are the most abundant cannabinoids and therefore the most studied.</p><p>However there are other minor cannabinoids such as delta-eight thc, <a href="https://mastodon.cr/tags/thca" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thca</span></a> , thcv, cbg, <a href="https://mastodon.cr/tags/cbn" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbn</span></a> , cbc which have been investigated to have therapeutic value (Izzo et al. 2009).</p><p>Although the compounds may have therapeutic effects taken alone (as in HEMP-derived isolate), their combined action when present together in whole plants (actually complete flower) extracts, is GREATER than the sum of their individual effects (up to 6x more potent according to recent studies). This enhanced and synergistic response is known as the <a href="https://mastodon.cr/tags/entourageeffect" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>entourageeffect</span></a> .</p><p>The combined action of cannabinoids and other molecules in the plant may present clinical advantages such as lower adverse effects and greater efficacy on the therapeutical management of several conditions, such as <a href="https://mastodon.cr/tags/anxiety" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>anxiety</span></a> , <a href="https://mastodon.cr/tags/depression" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>depression</span></a> , <a href="https://mastodon.cr/tags/pain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pain</span></a> , <a href="https://mastodon.cr/tags/inflammation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>inflammation</span></a> , <a href="https://mastodon.cr/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancer</span></a> and bacterial / fungi <a href="https://mastodon.cr/tags/infectiousdiseases" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>infectiousdiseases</span></a> </p><p>If other forms of healing interest you, beyond masking symptoms with synthetic proprietary mono-molecules, check this link for a more up-to-date text on cannabis and the entourage effect: <br> <a href="https://leafwell.com/blog/entourage-effect" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">leafwell.com/blog/entourage-ef</span><span class="invisible">fect</span></a></p><p><a href="https://mastodon.cr/tags/healthcare" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healthcare</span></a> <a href="https://mastodon.cr/tags/medical" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medical</span></a> <a href="https://mastodon.cr/tags/healthscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>healthscience</span></a> <a href="https://mastodon.cr/tags/marijuananews" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuananews</span></a> <a href="https://mastodon.cr/tags/marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>marijuana</span></a> <a href="https://mastodon.cr/tags/weed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>weed</span></a> <a href="https://mastodon.cr/tags/naturalist" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>naturalist</span></a> <br><a href="https://mastodon.cr/tags/cannabismedicinal" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabismedicinal</span></a> <a href="https://mastodon.cr/tags/herbalism" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>herbalism</span></a><br><a href="https://mastodon.cr/tags/solarpunk" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>solarpunk</span></a> <a href="https://mastodon.cr/tags/chronicillness" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chronicillness</span></a> <a href="https://mastodon.cr/tags/regenerativemedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>regenerativemedicine</span></a> <a href="https://mastodon.cr/tags/pain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pain</span></a><br><a href="https://mastodon.cr/tags/weed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>weed</span></a> <a href="https://mastodon.cr/tags/autoinmunedisease" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>autoinmunedisease</span></a> <a href="https://mastodon.cr/tags/medicalcrisis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicalcrisis</span></a> <a href="https://mastodon.cr/tags/herbalmedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>herbalmedicine</span></a></p>
JADe (he, him)<p>En años recientes se demostró que los cannabinoides ácidos, en flor cruda y seca de cannabis, no fumada ni cocinada, están cargados de propiedades terapéuticas.</p><p>Controlan el dolor crónico mejor que los antiiflamatorios no esteroideos (AINS como ibuprofeno, naproxeno, aspirina, etc) sin las hemorragias digestivas ni ulceras que estos a menudo provocan. </p><p>El THCa y el CBDa no son psicotrópicos pero ayudan con depresión, ansiedad, enfermedades autoinmunes, daño por contaminantes y muchas cosas más.</p><p>En este artículo enlazo estudios y explico porque su humilde flor es mejor medicina que los goteros industriales de <a href="https://mastodon.cr/tags/c%C3%A1%C3%B1amo" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cáñamo</span></a> <a href="https://mastodon.cr/tags/hemp" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hemp</span></a> y como hacer más efectivo su té herbal a partir de un estudio italiano del 2024.</p><p><a href="https://jorge-alban-dobles.blogspot.com/2023/07/bombo-cannabinoides-acidos-y-longevidad.html?m=1" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jorge-alban-dobles.blogspot.co</span><span class="invisible">m/2023/07/bombo-cannabinoides-acidos-y-longevidad.html?m=1</span></a></p><p>Espero sinceramente que en estas redes libres nos cuidemos un poco más el cuerpo/mente/corazón, no solo los equipos y el software. </p><p>Veo pocos tags funcionales sobre salud en @Mastodon, como si a la gran industria farmacéutica le importara en verdad nuestra salud y no fuera parte del corporativismo que mata y destruye el mundo "for a few dollars more".</p><p>Antes de caer en la danza macabra de los especialistas médicos, prueben con el té de cannabis por un par de semanas. El autocuido también es una forma de resistencia. </p><p><a href="https://mastodon.cr/tags/medicina" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicina</span></a> <a href="https://mastodon.cr/tags/cannabinoides" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoides</span></a> <a href="https://mastodon.cr/tags/autocuidado" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>autocuidado</span></a> <a href="https://mastodon.cr/tags/dolor" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>dolor</span></a> <a href="https://mastodon.cr/tags/padecimiento" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>padecimiento</span></a> <a href="https://mastodon.cr/tags/autoinmune" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>autoinmune</span></a><br><a href="https://mastodon.cr/tags/contaminacion" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>contaminacion</span></a> <a href="https://mastodon.cr/tags/solarpunk" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>solarpunk</span></a> <br><a href="https://mastodon.cr/tags/solarpunkaunday" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>solarpunkaunday</span></a> <a href="https://mastodon.cr/tags/selfcare" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>selfcare</span></a> <a href="https://mastodon.cr/tags/regenerativemedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>regenerativemedicine</span></a><br><a href="https://mastodon.cr/tags/medicalcannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>medicalcannabis</span></a> <a href="https://mastodon.cr/tags/weed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>weed</span></a> <a href="https://mastodon.cr/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a> <a href="https://mastodon.cr/tags/cbd" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbd</span></a> <a href="https://mastodon.cr/tags/cbda" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbda</span></a> <a href="https://mastodon.cr/tags/thca" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>thca</span></a></p>
JADe10x color microphotograph of overripe trichomes inside a cannabis flower.<br> <br> When those tiny glands start to turn brown it means oxidation is taking place and THC is turning into Cannabinol or CBN.<br> <br> After years of helping my octogenarian mother deal with chronic pain from her falls and titanium protesis I realized that CBN does most of the heavy lifting THC is credited for.<br> <br> To read the full story, and science behind it, follow the link to my blog. I have included the full recipe for cannabis cream, 6 years in the making.<br> <br> <a href="https://jorge--alban--dobles-blogspot-com.translate.goog/2025/02/mariguanol-para-la-abuela.html?m=1&amp;_x_tr_sl=auto&amp;_x_tr_tl=en&amp;_x_tr_hl=es&amp;_x_tr_pto=wapp" rel="nofollow noopener" target="_blank">https://jorge--alban--dobles-blogspot-com.translate.goog/2025/02/mariguanol-para-la-abuela.html?m=1&amp;_x_tr_sl=auto&amp;_x_tr_tl=en&amp;_x_tr_hl=es&amp;_x_tr_pto=wapp</a><br> <br> <a href="https://pixelfed.cr/discover/tags/medicalcannabis?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#medicalcannabis</a> <a href="https://pixelfed.cr/discover/tags/cannabismedicinal?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#cannabismedicinal</a><br> <a href="https://pixelfed.cr/discover/tags/cannabinoids?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#cannabinoids</a> <a href="https://pixelfed.cr/discover/tags/weed?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#weed</a> <a href="https://pixelfed.cr/discover/tags/marijuana?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#marijuana</a> <a href="https://pixelfed.cr/discover/tags/pain?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#pain</a><br> <a href="https://pixelfed.cr/discover/tags/paintherapy?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#paintherapy</a> <a href="https://pixelfed.cr/discover/tags/painmanagement?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#painmanagement</a> <a href="https://pixelfed.cr/discover/tags/dolor?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#dolor</a><br> <a href="https://pixelfed.cr/discover/tags/thirdage?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#thirdage</a> <a href="https://pixelfed.cr/discover/tags/olderpeople?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#olderpeople</a> <a href="https://pixelfed.cr/discover/tags/solarpunk?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#solarpunk</a> <a href="https://pixelfed.cr/discover/tags/regenerativemedicine?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#regenerativemedicine</a> <a href="https://pixelfed.cr/discover/tags/patients?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#patients</a> <a href="https://pixelfed.cr/discover/tags/thca?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#thca</a> <a href="https://pixelfed.cr/discover/tags/cbda?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#cbda</a> <a href="https://pixelfed.cr/discover/tags/thc?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#thc</a> <a href="https://pixelfed.cr/discover/tags/cbd?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#cbd</a> <a href="https://pixelfed.cr/discover/tags/terpenes?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#terpenes</a> <a href="https://pixelfed.cr/discover/tags/hemp?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#hemp</a> <a href="https://pixelfed.cr/discover/tags/stilllife?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#stilllife</a> <a href="https://pixelfed.cr/discover/tags/science?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#science</a> <br> <a href="https://pixelfed.cr/discover/tags/flowerpower?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#flowerpower</a> <a href="https://pixelfed.cr/discover/tags/nature?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#nature</a> <a href="https://pixelfed.cr/discover/tags/cbn?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#cbn</a> <a href="https://pixelfed.cr/discover/tags/naturephotography?src=hash" class="u-url hashtag" rel="nofollow noopener" target="_blank">#naturephotography</a>
Karl Theodor<p>Für <a href="https://mastodon.social/tags/Anw%C3%A4lte" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Anwälte</span></a> und <a href="https://mastodon.social/tags/Anw%C3%A4ltinnen" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Anwältinnen</span></a> und <a href="https://mastodon.social/tags/Klagende" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Klagende</span></a>: Wirklich evidente Informationen kann man da bekommen. Das sind die absoluten Spitzenleute, was die Forschung zu <a href="https://mastodon.social/tags/Cannabinoiden" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoiden</span></a> anbelangt.</p><p><a href="https://cannabis-med.org/de" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/de</span><span class="invisible"></span></a> [deutsch]</p><p><a href="https://cannabis-med.org/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/</span><span class="invisible"></span></a> [english]</p><p>The aim of the International Alliance for <a href="https://mastodon.social/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a> Medicines (<a href="https://mastodon.social/tags/IACM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>IACM</span></a>) is to advance knowledge on <a href="https://mastodon.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a>, <a href="https://mastodon.social/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a>, the <a href="https://mastodon.social/tags/endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoidsystem</span></a> and related topics, especially their therapeutic potential. <a href="https://mastodon.social/tags/Merz" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Merz</span></a> <a href="https://mastodon.social/tags/S%C3%B6der" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Söder</span></a> <a href="https://mastodon.social/tags/CarmenWegge" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CarmenWegge</span></a> <a href="https://mastodon.social/tags/ACM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ACM</span></a></p>
Karl Theodor<p>Für Anwälte und Anwältinnen und Klagende: Wirklich evidente Informationen kann man da bekommen. Das sind die absoluten Spitzenleute, was die Forschung zu <a href="https://mastodon.social/tags/Cannabinoiden" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoiden</span></a> anbelangt.</p><p><a href="https://cannabis-med.org/de" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/de</span><span class="invisible"></span></a> [deutsch]</p><p><a href="https://cannabis-med.org/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/</span><span class="invisible"></span></a> [english]</p><p>The aim of the International Alliance for <a href="https://mastodon.social/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a> Medicines (<a href="https://mastodon.social/tags/IACM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>IACM</span></a>) is to advance knowledge on <a href="https://mastodon.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a>, <a href="https://mastodon.social/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a>, the <a href="https://mastodon.social/tags/endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoidsystem</span></a> and related topics, especially their therapeutic potential.</p><p><a href="https://mastodon.social/tags/Bayern" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Bayern</span></a> <a href="https://mastodon.social/tags/Cannabisklage" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabisklage</span></a> <a href="https://mastodon.social/tags/Hanfwissen" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Hanfwissen</span></a></p>
JADe (he, him)<p><span class="h-card" translate="no"><a href="https://researchbuzz.masto.host/@researchbuzz" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>researchbuzz</span></a></span> </p><p>Nuevo estudio de YALE afirma que los cannabinoides, CBD, CBG y CBN podría dar alivio del dolor seguro, eficaz, sin efecto psicotrópico ni la fuerte dependencia de los opioides.</p><p><a href="https://news.yale.edu/2025/01/21/cannabinoids-offer-new-hope-safe-and-effective-pain-relief" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">news.yale.edu/2025/01/21/canna</span><span class="invisible">binoids-offer-new-hope-safe-and-effective-pain-relief</span></a></p><p><a href="https://mastodon.cr/tags/endomedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endomedicine</span></a> <a href="https://mastodon.cr/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> <a href="https://mastodon.cr/tags/cannabinoide" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoide</span></a> <a href="https://mastodon.cr/tags/cbdreceptors" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbdreceptors</span></a> <a href="https://mastodon.cr/tags/painmanagement" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>painmanagement</span></a> <a href="https://mastodon.cr/tags/cbn" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbn</span></a> <a href="https://mastodon.cr/tags/cbg" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cbg</span></a></p>
Karl Theodor<p><span class="h-card" translate="no"><a href="https://mastodon.social/@topgras" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>topgras</span></a></span> wirklich evidente Informationen kann man da bekommen. Das sind die absoluten Spitzenleute, was die Forschung zu <a href="https://mastodon.social/tags/Cannabinoiden" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoiden</span></a> anbelangt.</p><p><a href="https://cannabis-med.org/de" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/de</span><span class="invisible"></span></a> [deutsch]</p><p><a href="https://cannabis-med.org/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">cannabis-med.org/</span><span class="invisible"></span></a> [english]</p><p>The aim of the International Alliance for <a href="https://mastodon.social/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoid</span></a> Medicines (<a href="https://mastodon.social/tags/IACM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>IACM</span></a>) is to advance knowledge on <a href="https://mastodon.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a>, <a href="https://mastodon.social/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a>, the <a href="https://mastodon.social/tags/endocannabinoidsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoidsystem</span></a> and related topics, especially their therapeutic potential.</p><p><a href="https://mastodon.social/tags/Hanf" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Hanf</span></a> <a href="https://mastodon.social/tags/Weed" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Weed</span></a> <a href="https://mastodon.social/tags/Wissenschaft" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Wissenschaft</span></a> <a href="https://mastodon.social/tags/Medizin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Medizin</span></a> <a href="https://mastodon.social/tags/Wissen" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Wissen</span></a> <a href="https://mastodon.social/tags/Evidenz" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Evidenz</span></a> <a href="https://mastodon.social/tags/Marijuana" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Marijuana</span></a></p>
N95Bias Ⓥ🏴‍☠️<p>Nasal sprays might help protect the upper respiratory tract, but what about the lungs? What if we had something we could vaporize and fill the lungs with that might raise the minimum infectious dose of SARSCoV2 by inhibiting cell entry?</p><p>Something that isn't psychoactive -- like CBD -- and could be used by everyone? What if regulated, plentiful, and inexpensive CBD extract could be found at every pharmacy?</p><p>"Retrospective clinical studies support antiviral activities of CBD, Δ9-THC, and cannabinoid mixtures as do some prospective clinical trials, but appropriately designed clinical trials of safety and efficacy of antiviral cannabinoids are urgently needed."</p><p><a href="https://portlandpress.com/clinsci/article/137/8/633/232928/Antiviral-activities-of-hemp-cannabinoids" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">portlandpress.com/clinsci/arti</span><span class="invisible">cle/137/8/633/232928/Antiviral-activities-of-hemp-cannabinoids</span></a></p><p><a href="https://zeroes.ca/tags/SARSCoV2" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SARSCoV2</span></a> <a href="https://zeroes.ca/tags/covid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>covid</span></a> <a href="https://zeroes.ca/tags/covid19" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>covid19</span></a> <a href="https://zeroes.ca/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CBD</span></a> <a href="https://zeroes.ca/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a> <a href="https://zeroes.ca/tags/PublicHealth" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PublicHealth</span></a> <a href="https://zeroes.ca/tags/CovidIsNotOver" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CovidIsNotOver</span></a></p>
Xamanismo Coletivo<p>"<a href="https://hachyderm.io/tags/CarlSagan" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CarlSagan</span></a>, the astronomer &amp; science communicator, speculated that <a href="https://hachyderm.io/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabis</span></a> might be the 1st ever domesticated plant, the one that drove the dawn of <a href="https://hachyderm.io/tags/agriculture" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>agriculture</span></a>. The <a href="https://hachyderm.io/tags/endocannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoid</span></a> system, that regulates other systems in the human body, is where <a href="https://hachyderm.io/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> like <a href="https://hachyderm.io/tags/THC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>THC</span></a> fit like a lock &amp; a key. This is how foundational a relationship can get… you have to love that plant a whole lot to create agriculture simply to have a steady supply."<br><a href="https://pca.st/wjj3qblb?t=20m8s" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">pca.st/wjj3qblb?t=20m8s</span><span class="invisible"></span></a></p>
DoomsdaysCW<p><a href="https://kolektiva.social/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> as novel <a href="https://kolektiva.social/tags/AntiInflammatory" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AntiInflammatory</span></a> drugs</p><p>by Prakash Nagarkatti, et al.<br>October, 2009</p><p>Abstract:</p><p>"Cannabinoids are a group of compounds that mediate their effects through cannabinoid receptors. The discovery of Δ9-tetrahydrocannabinol (<a href="https://kolektiva.social/tags/THC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>THC</span></a>) as the major psychoactive principle in marijuana, as well as the identification of <a href="https://kolektiva.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoid</span></a> receptors and their endogenous ligands, has led to a significant growth in research aimed at understanding the physiological functions of cannabinoids. Cannabinoid receptors include CB1, which is predominantly expressed in the brain, and CB2, which is primarily found on the cells of the immune system. The fact that both CB1 and CB2 receptors have been found on <a href="https://kolektiva.social/tags/immune" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>immune</span></a> cells suggests that cannabinoids play an important role in the regulation of the immune system. Recent studies demonstrated that administration of THC into mice triggered marked apoptosis in T cells and dendritic cells, resulting in immunosuppression. In addition, several studies showed that cannabinoids downregulate <a href="https://kolektiva.social/tags/cytokine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cytokine</span></a> and chemokine production and, in some models, upregulate T-regulatory cells (Tregs) as a mechanism to suppress <a href="https://kolektiva.social/tags/inflammatory" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>inflammatory</span></a> responses. The <a href="https://kolektiva.social/tags/endocannabinoid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>endocannabinoid</span></a> system is also involved in <a href="https://kolektiva.social/tags/immunoregulation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>immunoregulation</span></a>. For example, administration of endocannabinoids or use of inhibitors of enzymes that break down the endocannabinoids, led to immunosuppression and recovery from immune-mediated injury to organs such as the liver. Manipulation of endocannabinoids and/or use of exogenous cannabinoids in vivo can constitute a potent treatment modality against inflammatory disorders. This review will focus on the potential use of cannabinoids as a new class of anti-inflammatory agents against a number of inflammatory and autoimmune diseases that are primarily triggered by activated T cells or other cellular immune components."</p><p>Executive summary</p><p>- Cannabinoids, the active components of <a href="https://kolektiva.social/tags/CannabisSativa" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CannabisSativa</span></a>, and endogenous cannabinoids mediate their effects through activation of specific cannabinoid receptors known as cannabinoid receptor 1 and 2 (CB1 and CB2).</p><p>- The cannabinoid system has been shown both in vivo and in vitro to be involved in regulating the immune system through its immunomodulatory properties.</p><p>- Cannabinoids suppress inflammatory response and subsequently attenuate disease symptoms. This property of cannabinoids is mediated through multiple pathways such as induction of apoptosis in activated immune cells, suppression of cytokines and chemokines at inflammatory sites and upregulation of FoxP3+ regulatory T cells.</p><p>- Cannabinoids have been tested in several experimental models of autoimmune disorders such as <a href="https://kolektiva.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a>, <a href="https://kolektiva.social/tags/RheumatoidArthritis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RheumatoidArthritis</span></a>, <a href="https://kolektiva.social/tags/colitis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>colitis</span></a> and <a href="https://kolektiva.social/tags/hepatitis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hepatitis</span></a> and have been shown to protect the host from the pathogenesis through induction of multiple anti-inflammatory pathways.</p><p>- Cannabinoids may also be beneficial in certain types of <a href="https://kolektiva.social/tags/cancers" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancers</span></a> that are triggered by <a href="https://kolektiva.social/tags/ChronicInflammation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ChronicInflammation</span></a> In such instances, cannabinoids can either directly inhibit tumor growth or suppress inflammation and tumor angiogenesis.</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">ncbi.nlm.nih.gov/pmc/articles/</span><span class="invisible">PMC2828614/</span></a></p>
rexi<p><a href="https://www.forbes.com/sites/ajherrington/2024/01/11/study-shows-cannabis-has-the-potential-to-prevent-and-treat-covid-19/?sh=48c621fa2574" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">forbes.com/sites/ajherrington/</span><span class="invisible">2024/01/11/study-shows-cannabis-has-the-potential-to-prevent-and-treat-covid-19/?sh=48c621fa2574</span></a></p><p>@dalhousie_university researchers:“Cannabinoids have the potential to be used as a preventive approach to limiting the susceptibility and severity of <a href="https://mastodon.social/tags/COVID19" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>COVID19</span></a> infections by preventing viral entry, mitigating oxidative stress, and alleviating the associated <a href="https://mastodon.social/tags/cytokinestorm" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cytokinestorm</span></a>.”</p><p>study also found they could be used to treat patients with <a href="https://mastodon.social/tags/LongCovid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>LongCovid</span></a>…“Post- <a href="https://mastodon.social/tags/SarsCoV2" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SarsCoV2</span></a> infection, <a href="https://mastodon.social/tags/cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cannabinoids</span></a> have shown promise in treating symptoms associated with post-acute long COVID-19…"</p>
eLife<p><a href="https://fediscience.org/tags/Cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabis</span></a> consumption in pregnant women has almost doubled in recent years. Scientists are looking at mice to start investigating the effects of <a href="https://fediscience.org/tags/THC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>THC</span></a> on embryonic cells. <a href="https://fediscience.org/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cannabinoids</span></a> <a href="https://elifesciences.org/digests/88795/the-impact-of-cannabis-on-mouse-embryonic-cells?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">elifesciences.org/digests/8879</span><span class="invisible">5/the-impact-of-cannabis-on-mouse-embryonic-cells?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic</span></a></p>