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DigitAre you <a href="https://autistics.life/tags/ActuallyAutistic" class="mention hashtag" rel="nofollow noopener" target="_blank">#ActuallyAutistic</a> ? Tried <a href="https://autistics.life/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> ( <a href="https://autistics.life/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a> ) to help with self regulation?

ND Dev<a href="https://aus.social/@joannaholman" class="u-url mention" rel="nofollow noopener" target="_blank">@joannaholman</a> People have given excellent tips on this thread. Let me give a more controversial one: if it's legal where you are, consider taking <a href="https://infosec.space/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> (<a href="https://infosec.space/tags/cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabidiol</a>). If you can get it, a broad-spectrum variety will work better but be a bit more expensive. It's not addictive and it won't get you high, but I find it takes the edge off high-stimulation events. If you're <a href="https://infosec.space/tags/ActuallyAutistic" class="mention hashtag" rel="nofollow noopener" target="_blank">#ActuallyAutistic</a>, as I am, then your body may well be short of endocannabinoids (chemicals made by the body that mimic the action of cannabis). In that case, a small dose of CBD will only be taking you up to the same level as everyone else at the conferences.<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6354384/" rel="nofollow noopener" translate="no" target="_blank">https://pmc.ncbi.nlm.nih.gov/articles/PMC6354384/</a>Try it out before you go, and start with a really low dose, such as five or ten milligrammes, just in case it disagrees with you.Good luck! I hope the conferences go well for you.

LaufbloggerArchiv: <a href="https://mastodon.social/tags/CBG" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBG</a> Öl: Was ist <a href="https://mastodon.social/tags/Cannabigerol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabigerol</a> und was ist der Unterschied zu <a href="https://mastodon.social/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a> und CBD? <a href="https://www.sports-insider.de/cbg-oel-was-ist-cannabigerol-und-was-ist-der-unterschied-zu-cannabidiol-und-cbd-45229/" rel="nofollow noopener" translate="no" target="_blank">https://www.sports-insider.de/cbg-oel-was-ist-cannabigerol-und-was-ist-der-unterschied-zu-cannabidiol-und-cbd-45229/</a> <a href="https://mastodon.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://mastodon.social/tags/Hanf%C3%B6l" class="mention hashtag" rel="nofollow noopener" target="_blank">#Hanföl</a> <a href="https://mastodon.social/tags/Hanf" class="mention hashtag" rel="nofollow noopener" target="_blank">#Hanf</a> <a href="https://mastodon.social/tags/CBD%C3%96l" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBDÖl</a> <a href="https://mastodon.social/tags/CBG%C3%96l" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBGÖl</a>

GehtsoErnährung Wie gefährlich sind CBD-haltige Lebensmittel? Dosierung von Cannabidiol entscheidet über Nutzen und Risiken <a href="https://www.scinexx.de/news/medizin/wie-gefaehrlich-sind-cbd-haltige-lebensmittel/" rel="nofollow noopener" translate="no" target="_blank">https://www.scinexx.de/news/medizin/wie-gefaehrlich-sind-cbd-haltige-lebensmittel/</a><a href="https://social.tchncs.de/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://social.tchncs.de/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a> <a href="https://social.tchncs.de/tags/THC" class="mention hashtag" rel="nofollow noopener" target="_blank">#THC</a> <a href="https://social.tchncs.de/tags/Lebensmittel" class="mention hashtag" rel="nofollow noopener" target="_blank">#Lebensmittel</a> <a href="https://social.tchncs.de/tags/Cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabis</a> <a href="https://social.tchncs.de/tags/Deutschland" class="mention hashtag" rel="nofollow noopener" target="_blank">#Deutschland</a>

scinexx - das wissensmagazinWie gefährlich sind CBD-haltige Lebensmittel? Cannabidiol-Produkte halten nicht, womit die Hersteller werben. <a href="https://nrw.social/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a> <a href="https://nrw.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://nrw.social/tags/CBDOel" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBDOel</a> <a href="https://nrw.social/tags/Hanf" class="mention hashtag" rel="nofollow noopener" target="_blank">#Hanf</a> <a href="https://www.scinexx.de/news/medizin/wie-gefaehrlich-sind-cbd-haltige-lebensmittel/" rel="nofollow noopener" translate="no" target="_blank">https://www.scinexx.de/news/medizin/wie-gefaehrlich-sind-cbd-haltige-lebensmittel/</a>

PsyPostCBD shows promise in managing fever and inflammation <a href="https://www.psypost.org/cbd-shows-promise-in-managing-fever-and-inflammation/?utm_source=dlvr.it&utm_medium=mastodon" rel="nofollow noopener" translate="no" target="_blank">https://www.psypost.org/cbd-shows-promise-in-managing-fever-and-inflammation/?utm_source=dlvr.it&utm_medium=mastodon</a> <a href="https://mstdn.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://mstdn.social/tags/fever" class="mention hashtag" rel="nofollow noopener" target="_blank">#fever</a> <a href="https://mstdn.social/tags/inflammation" class="mention hashtag" rel="nofollow noopener" target="_blank">#inflammation</a> <a href="https://mstdn.social/tags/cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabidiol</a> <a href="https://mstdn.social/tags/immune" class="mention hashtag" rel="nofollow noopener" target="_blank">#immune</a>

RoedigerRGWe will be presenting 3 posters at the <a href="https://social.anoxinon.de/tags/DGKMH" class="mention hashtag" rel="nofollow noopener" target="_blank">#DGKMH</a> in November 2024, <a href="https://social.anoxinon.de/tags/senftenberg" class="mention hashtag" rel="nofollow noopener" target="_blank">#senftenberg</a> 1: "Early detection of <a href="https://social.anoxinon.de/tags/neurodegenerative" class="mention hashtag" rel="nofollow noopener" target="_blank">#neurodegenerative</a> diseases by multiplex analysis of specific biomarkers using fluorescent microparticles" 2: "Behavioral Differences in Hybridization and Melting Profiles Following Covalent vs. Non-Covalent Oligonucleotide Coupling to <a href="https://social.anoxinon.de/tags/Microbeads" class="mention hashtag" rel="nofollow noopener" target="_blank">#Microbeads</a> via Crosslinkers and Biotin" 3: "<a href="https://social.anoxinon.de/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a> Does Not Cause DNA Double Strand Breaks in a Human Liver Derived Cell Model"<a href="https://social.anoxinon.de/@RoedigerRG/113225324444229632" rel="nofollow noopener" translate="no" target="_blank">https://social.anoxinon.de/@RoedigerRG/113225324444229632</a>

formuchdeliberationScientists Found a Cannabis Compound Inside a Totally Different Plant : ScienceAlert…Scientists have discovered cannabidiol, a compound in cannabis known as CBD, in a common Brazilian plant, opening potential new avenues to produce the increasingly popular substance... Science Alert <a href="https://mastodon.world/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://mastodon.world/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabis</a> <a href="https://mastodon.world/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#health</a> <a href="https://mastodon.world/tags/medicalresearch" class="mention hashtag" rel="nofollow noopener" target="_blank">#medicalresearch</a> <a href="https://mastodon.world/tags/cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabidiol</a><a href="https://formuchdeliberation.wordpress.com/2024/10/06/scientists-found-a-cannabis-compound-inside-a-totally-different-plant-sciencealert/" rel="nofollow noopener" translate="no" target="_blank">https://formuchdeliberation.wordpress.com/2024/10/06/scientists-found-a-cannabis-compound-inside-a-totally-different-plant-sciencealert/</a>

Gute Pillen – Schlechte PillenDer Cannabis-Wirkstoff <a href="https://mastodon.social/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a> wird in unzähligen Produkten als „natürliches“ Heilmittel angepriesen. Wenn Sie Medikamente einnehmen, ist jedoch Vorsicht geboten. (€)<a href="https://buff.ly/4g1c67l" rel="nofollow noopener" translate="no" target="_blank">https://buff.ly/4g1c67l</a>

PlanetMedicinesCannabidiol or ketamine for preventing the impact of adolescent early drug initiation on voluntary ethanol consumption in adulthood (Colom-Rocha, et al, 2024) <a href="https://pubmed.ncbi.nlm.nih.gov/39257392/" rel="nofollow noopener" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/39257392/</a> <a href="https://toad.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener" target="_blank">#ketamine</a> <a href="https://toad.social/tags/cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabidiol</a>

Matt WillemsenScientists Find a Cannabis Compound Inside Totally Different Plant <a href="https://www.sciencealert.com/scientists-find-a-cannabis-compound-inside-totally-different-plant" rel="nofollow noopener" translate="no" target="_blank">https://www.sciencealert.com/scientists-find-a-cannabis-compound-inside-totally-different-plant</a> <a href="https://mastodon.social/tags/drugs" class="mention hashtag" rel="nofollow noopener" target="_blank">#drugs</a> <a href="https://mastodon.social/tags/brazil" class="mention hashtag" rel="nofollow noopener" target="_blank">#brazil</a> <a href="https://mastodon.social/tags/cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabidiol</a> <a href="https://mastodon.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://mastodon.social/tags/TremaMicranthaBlume" class="mention hashtag" rel="nofollow noopener" target="_blank">#TremaMicranthaBlume</a>

Mikko Lehtovirta<a href="https://mastodontti.fi/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> eli <a href="https://mastodontti.fi/tags/kannabidioli" class="mention hashtag" rel="nofollow noopener" target="_blank">#kannabidioli</a> on vain ja ainoastaan sellainen <a href="https://mastodontti.fi/tags/k%C3%A4%C3%A4rme%C3%B6ljy" class="mention hashtag" rel="nofollow noopener" target="_blank">#käärmeöljy</a> jollaiselta se on alunperinkin vaikuttanut.<a href="https://mastodontti.fi/tags/cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabidiol</a> <a href="https://mastodontti.fi/tags/snakeoil" class="mention hashtag" rel="nofollow noopener" target="_blank">#snakeoil</a> <a href="https://mastodontti.fi/tags/usasp" class="mention hashtag" rel="nofollow noopener" target="_blank">#usasp</a> <a href="https://mastodontti.fi/tags/journalofpain" class="mention hashtag" rel="nofollow noopener" target="_blank">#journalofpain</a> <a href="https://www.jpain.org/article/S1526-5900(23)00582-5/fulltext" rel="nofollow noopener" translate="no" target="_blank">https://www.jpain.org/article/S1526-5900(23)00582-5/fulltext</a>

DoomsdaysCW<a href="https://kolektiva.social/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a> (<a href="https://kolektiva.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a>): a killer for <a href="https://kolektiva.social/tags/inflammatory" class="mention hashtag" rel="nofollow noopener" target="_blank">#inflammatory</a> rheumatoid <a href="https://kolektiva.social/tags/arthritis" class="mention hashtag" rel="nofollow noopener" target="_blank">#arthritis</a> synovial fibroblastsPublished: 01 September 2020 by Torsten Lowin, et al.Abstract:"Cannabidiol (CBD) is a non-intoxicating phytocannabinoid from cannabis sativa that has demonstrated anti-inflammatory effects in several inflammatory conditions including arthritis. However, CBD binds to several receptors and enzymes and, therefore, its mode of action remains elusive. In this study, we show that CBD increases intracellular calcium levels, reduces cell viability and IL-6/IL-8/MMP-3 production of rheumatoid arthritis synovial fibroblasts (RASF). These effects were pronounced under inflammatory conditions by activating transient receptor potential ankyrin (TRPA1), and by opening of the mitochondrial permeability transition pore. Changes in intracellular calcium and cell viability were determined by using the fluorescent dyes Cal-520/PoPo3 together with cell titer blue and the luminescent dye RealTime-glo. Cell-based impedance measurements were conducted with the XCELLigence system and TRPA1 protein was detected by flow cytometry. Cytokine production was evaluated by ELISA. CBD reduced cell viability, proliferation, and IL-6/IL-8 production of RASF. Moreover, CBD increased intracellular calcium and uptake of the cationic viability dye PoPo3 in RASF, which was enhanced by pre-treatment with TNF. Concomitant incubation of CBD with the TRPA1 antagonist A967079 but not the TRPV1 antagonist capsazepine reduced the effects of CBD on calcium and PoPo3 uptake. In addition, an inhibitor of the mitochondrial permeability transition pore, cyclosporin A, also blocked the effects of CBD on cell viability and IL-8 production. PoPo3 uptake was inhibited by the voltage-dependent anion-selective channel inhibitor DIDS and Decynium-22, an inhibitor for all organic cation transporter isoforms. CBD increases intracellular calcium levels, reduces cell viability, and IL-6/IL-8/MMP-3 production of RASF by activating TRPA1 and mitochondrial targets. This effect was enhanced by pre-treatment with TNF suggesting that CBD preferentially targets activated, pro-inflammatory RASF. Thus, CBD possesses anti-arthritic activity and might ameliorate arthritis via targeting synovial fibroblasts under inflammatory conditions."Source: <a href="https://www.nature.com/articles/s41419-020-02892-1" rel="nofollow noopener" translate="no" target="_blank">https://www.nature.com/articles/s41419-020-02892-1</a> <a href="https://kolektiva.social/tags/Cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabis</a> <a href="https://kolektiva.social/tags/AntiInflammatory" class="mention hashtag" rel="nofollow noopener" target="_blank">#AntiInflammatory</a>

C++ guyThe FSA, the UK's food regulator, has reduced the maximum recommended dose of <a class="hashtag" href="https://outerheaven.club/tag/cbd" rel="nofollow noopener" target="_blank">#cbd</a> <a class="hashtag" href="https://outerheaven.club/tag/cannabidiol" rel="nofollow noopener" target="_blank">#cannabidiol</a> from 70mg a day to just 10mg a day, citing risks to the liver and thyroid: BBC News - Cannabidiol safe daily dose limit cut by food regulator <a href="https://www.bbc.co.uk/news/health-67087470" rel="nofollow noopener" target="_blank">https://www.bbc.co.uk/news/health-67087470</a> I'll comply, but it'll make my sleep even worse. 😟

idw_online<a href="https://idw-online.social/tags/Cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabis</a>-Wirkstoff gegen Darmentzündung: Forschende vom Fachbereich <a href="https://idw-online.social/tags/Veterin%C3%A4rmedizin" class="mention hashtag" rel="nofollow noopener" target="_blank">#Veterinärmedizin</a> der @FU_Berlin entschlüsseln Wirkung von <a href="https://idw-online.social/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a> <a href="https://nachrichten.idw-online.de/2023/09/29/cannabis-wirkstoff-gegen-darmentzuendung-forschende-der-freien-universitaet-berlin-entschluesseln-wirkung-von-cannabidiol" rel="nofollow noopener" target="_blank">https://nachrichten.idw-online.de/2023/09/29/cannabis-wirkstoff-gegen-darmentzuendung-forschende-der-freien-universitaet-berlin-entschluesseln-wirkung-von-cannabidiol</a>

Marine Mas, PhD(diapos du Dr QUEUILLE) En ccl: faites attention aux interactions avec les médicaments (psychotropes tels que Seroplex, Atharax; Methadone, mais aussi non-psychotropes car risque hémorragique avec certains anti-coagulants par exemple). Les produits ne sont pas toujours conformes à l'étiquetage donc compliqué d'évaluer le risque systématiquement. Prêter attention au mode de consommation qui influe largement sur la pharmacocinétique. <a href="https://sciences.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://sciences.social/tags/Psychotropes" class="mention hashtag" rel="nofollow noopener" target="_blank">#Psychotropes</a> <a href="https://sciences.social/tags/addicto" class="mention hashtag" rel="nofollow noopener" target="_blank">#addicto</a> <a href="https://sciences.social/tags/cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabidiol</a>

Marine Mas, PhDSéminaire Cannabidiol & Traitements psychotropes organisé par Prépsy, c'est maintenant! <a href="https://sciences.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://sciences.social/tags/Psychotropes" class="mention hashtag" rel="nofollow noopener" target="_blank">#Psychotropes</a> <a href="https://sciences.social/tags/addicto" class="mention hashtag" rel="nofollow noopener" target="_blank">#addicto</a> <a href="https://sciences.social/tags/cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabidiol</a>

Matt WillemsenThe Healing Power of Cannabis – Scientists Shed New Light on Its Anti-Inflammatory Effects Researchers from the Institute of Pharmacy in Jena studied the anti-inflammatory effects of cannabinoids, particularly focusing on CBD (cannabidiol). They found that CBD activates an enzyme leading to inflammation resolution and believe these findings could result in new treatments for inflammatory diseases. <a href="https://scitechdaily.com/the-healing-power-of-cannabis-scientists-shed-new-light-on-its-anti-inflammatory-effects/" rel="nofollow noopener" target="_blank">https://scitechdaily.com/the-healing-power-of-cannabis-scientists-shed-new-light-on-its-anti-inflammatory-effects/</a> <a href="https://fedibird.com/tags/cannabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabis</a> <a href="https://fedibird.com/tags/pharmaceutical" class="mention hashtag" rel="nofollow noopener" target="_blank">#pharmaceutical</a> <a href="https://fedibird.com/tags/AntiInflammatory" class="mention hashtag" rel="nofollow noopener" target="_blank">#AntiInflammatory</a> <a href="https://fedibird.com/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://fedibird.com/tags/cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#cannabidiol</a> <a href="https://fedibird.com/tags/enzyme" class="mention hashtag" rel="nofollow noopener" target="_blank">#enzyme</a> <a href="https://fedibird.com/tags/15lipoxygenase1" class="mention hashtag" rel="nofollow noopener" target="_blank">#15lipoxygenase1</a>

scinexx - das wissensmagazinWie Hanf heilen hilft. Wirkmechanismus von Cannabinoiden wie CBD gegen Entzündungen aufgeklärt. <a href="https://nrw.social/tags/CBD" class="mention hashtag" rel="nofollow noopener" target="_blank">#CBD</a> <a href="https://nrw.social/tags/Canabis" class="mention hashtag" rel="nofollow noopener" target="_blank">#Canabis</a> <a href="https://nrw.social/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a> <a href="https://nrw.social/tags/Entzuendung" class="mention hashtag" rel="nofollow noopener" target="_blank">#Entzuendung</a> <a href="https://nrw.social/tags/Immunsystem" class="mention hashtag" rel="nofollow noopener" target="_blank">#Immunsystem</a> <a href="https://www.scinexx.de/news/medizin/wie-hanf-heilen-hilft/" rel="nofollow noopener" target="_blank">https://www.scinexx.de/news/medizin/wie-hanf-heilen-hilft/</a>

ℵ₀ 🏳️‍⚧️🏴‍☠️Structure–Activity Relationship <a href="https://mastodon.social/tags/Study" class="mention hashtag" rel="nofollow noopener" target="_blank">#Study</a> of <a href="https://mastodon.social/tags/Cannabidiol" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cannabidiol</a>-Based <a href="https://mastodon.social/tags/Analogs" class="mention hashtag" rel="nofollow noopener" target="_blank">#Analogs</a> as Negative <a href="https://mastodon.social/tags/Allosteric" class="mention hashtag" rel="nofollow noopener" target="_blank">#Allosteric</a> <a href="https://mastodon.social/tags/Modulators" class="mention hashtag" rel="nofollow noopener" target="_blank">#Modulators</a> of the μ-<a href="https://mastodon.social/tags/Opioid" class="mention hashtag" rel="nofollow noopener" target="_blank">#Opioid</a> <a href="https://mastodon.social/tags/Receptor" class="mention hashtag" rel="nofollow noopener" target="_blank">#Receptor</a><a href="https://pubs.acs.org/doi/epdf/10.1021/acs.jmedchem.3c00061" rel="nofollow noopener" translate="no" target="_blank">https://pubs.acs.org/doi/epdf/10.1021/acs.jmedchem.3c00061</a>“The US faces an unprecedented surge in fatal drug overdoses. Naloxone, the only antidote for opiate overdose, competes at the mu opioid receptor (μOR) orthosteric site. Naloxone struggles against fentanyl-class synthetic opioids that now cause ∼80% of deaths.”

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