@schlink I just switched to Mutt a couple of weeks ago, and I've been really enjoying it so far. I think it really shines when combined with email in an offline database with mbsync or similar—that way, you have a full archive/backup and can work offline if necessary.
My setup uses mbsync to make a local maildir for a couple of accounts, Mutt as the mail client, and Mu for searching/indexing, loosely inspired by https://webgefrickel.de/blog/a-modern-mutt-setup (though without some of the more advanced setup (yet!))