It's really about the right tool for the job. I've used Python but C# scripting feels more natural and is almost as productive on Windows (at work). It's also supported by our IT.
My personal favorite is Lua but eventually that gets ported to something else. I've done batch files to Java depending on the goal. VBA is a staple in my field. I've done hot-key scripts is AutoIt to visual automation with commercial software.
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